{"title":"稳定型高碳酸血症性COPD的鼻高流量与无创通气:初步报告。","authors":"Jens Bräunlich, Hans-Jürgen Seyfarth, Hubert Wirtz","doi":"10.1186/s40248-015-0019-y","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>There are no data available about effectiveness of Nasal High-flow (NHF)in chronic respiratory insufficiency.</p><p><strong>Methods: </strong>Eleven COPD patients with stable hypercapnia were adjusted to NHF-system with a flow of 20 l/min. After six weeks patients were switched to non-invasive ventilation (NIV) for another six weeks period.</p><p><strong>Results: </strong>NHF led to significant decreases in resting pCO2. Between the devices we found no differences in pCO2 levels.</p><p><strong>Conclusions: </strong>NHF may thus be an alternative treatment device in stable hypercapnic COPD patients.</p>","PeriodicalId":49031,"journal":{"name":"Multidisciplinary Respiratory Medicine","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2015-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40248-015-0019-y","citationCount":"72","resultStr":"{\"title\":\"Nasal High-flow versus non-invasive ventilation in stable hypercapnic COPD: a preliminary report.\",\"authors\":\"Jens Bräunlich, Hans-Jürgen Seyfarth, Hubert Wirtz\",\"doi\":\"10.1186/s40248-015-0019-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>There are no data available about effectiveness of Nasal High-flow (NHF)in chronic respiratory insufficiency.</p><p><strong>Methods: </strong>Eleven COPD patients with stable hypercapnia were adjusted to NHF-system with a flow of 20 l/min. After six weeks patients were switched to non-invasive ventilation (NIV) for another six weeks period.</p><p><strong>Results: </strong>NHF led to significant decreases in resting pCO2. Between the devices we found no differences in pCO2 levels.</p><p><strong>Conclusions: </strong>NHF may thus be an alternative treatment device in stable hypercapnic COPD patients.</p>\",\"PeriodicalId\":49031,\"journal\":{\"name\":\"Multidisciplinary Respiratory Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2015-09-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1186/s40248-015-0019-y\",\"citationCount\":\"72\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Multidisciplinary Respiratory Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s40248-015-0019-y\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2015/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Multidisciplinary Respiratory Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s40248-015-0019-y","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2015/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Nasal High-flow versus non-invasive ventilation in stable hypercapnic COPD: a preliminary report.
Background: There are no data available about effectiveness of Nasal High-flow (NHF)in chronic respiratory insufficiency.
Methods: Eleven COPD patients with stable hypercapnia were adjusted to NHF-system with a flow of 20 l/min. After six weeks patients were switched to non-invasive ventilation (NIV) for another six weeks period.
Results: NHF led to significant decreases in resting pCO2. Between the devices we found no differences in pCO2 levels.
Conclusions: NHF may thus be an alternative treatment device in stable hypercapnic COPD patients.
期刊介绍：
Multidisciplinary Respiratory Medicine is the official journal of the Italian Respiratory Society - Società Italiana di Pneumologia (IRS/SIP). The journal publishes on all aspects of respiratory medicine and related fields, with a particular focus on interdisciplinary and translational research.
The interdisciplinary nature of the journal provides a unique opportunity for researchers, clinicians and healthcare professionals across specialties to collaborate and exchange information. The journal provides a high visibility platform for the publication and dissemination of top quality original scientific articles, reviews and important position papers documenting clinical and experimental advances.
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