由模仿肺结核的克雷伯氏菌引起的慢性肺炎。

Kamal Gera, Rahul Roshan, Mandira Varma-Basil, Ashok Shah
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引用次数: 8

摘要

克雷伯菌很少引起急性社区获得性肺炎(CAP)。由肺炎克雷伯菌(弗里德兰德氏杆菌)引起的慢性形式的疾病在抗生素前时代偶尔可见。氧曲菌是一种非常罕见的CAP病因。由氧曲菌引起的慢性形式的疾病以前只记录过一次。一个50岁的免疫功能正常的男性吸烟者提出了咯血12个月。影像学显示右上叶有空洞病变伴肺气肿改变。痰液染色及结核分枝杆菌培养均为阴性。然而,三份需氧培养的痰液样本和支气管抽吸培养的痰液样本都培养出了纯的氧梭菌。诊断为慢性肺炎,由于克雷伯菌是建立和适当的治疗,病人在很大程度上无症状。慢性克雷伯菌肺炎在临床和影像学上与肺结核的显著相似,可导致患者错误地接受抗结核治疗。
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Chronic pneumonia due to Klebsiella oxytoca mimicking pulmonary tuberculosis.

Klebsiella species infrequently cause acute community acquired pneumonia (CAP). The chronic form of the disease caused by K. pneumoniae (Friedlander's bacillus) was occasionally seen in the pre-antibiotic era. K. oxytoca is a singularly uncommon cause of CAP. The chronic form of the disease caused by K. oxytoca has been documented only once before. A 50-year-old immunocompetent male smoker presented with haemoptysis for 12 months. Imaging demonstrated a cavitary lesion in the right upper lobe with emphysematous changes. Sputum stains and cultures for Mycobacterium tuberculosis were negative. However, three sputum samples for aerobic culture as well as bronchial aspirate cultured pure growth of K. oxytoca. A diagnosis of chronic pneumonia due to K. oxytoca was established and with appropriate therapy, the patient was largely asymptomatic. The remarkable clinical and radiological similarity to pulmonary tuberculosis can result in patients with chronic Klebsiella pneumonia erroneously receiving anti-tuberculous therapy.

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