[代谢纠正:对抗疾病的生化选择]。

Jorge R Miranda-Massari, Michael J González, José R Rodriguez-Gomez, Jorge Duconge, Myriam Z Allende-Vigo, Francisco J Jiménez Ramirez, Kenneth Cintrón, Carlos Ricart, Rafael Zaragoza-Urdaz, Miguel Jabbar Berdiel, Alex Vázquez
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引用次数: 0

摘要

人类的发育及其生理取决于许多复杂的生物化学身体过程,其中许多是相互作用和相互依赖的。许多生理反应完成的速度和程度取决于酶的活性,而酶的活性又取决于辅助因子和微量营养素(如维生素和矿物质)的生物利用度。为了达到一个健康的生理状态,生物体需要生化反应以一种受控的、特定的方式、特定的速度和完全完成的水平或等级进行。要做到这一点,需要一个最佳的代谢平衡。诸如特定的基因组成、不适当的饮食消费模式、创伤、疾病、毒素和环境压力等因素,所有这些因素都增加了对营养素的需求,以获得最佳的代谢平衡。代谢校正是一个生物化学和生理学的概念,它解释了生物体细胞生物化学的改善如何帮助身体实现代谢和生理的优化。我们总结了几位先驱者在理解微量营养素在健康管理中的作用方面的贡献。由于存在影响酶反应速度的遗传变异,导致代谢改变,从而增强或促进多种疾病的状态/发展,代谢纠正的概念正在成为一个重要的术语。我们所吃食物的营养价值下降,正常发育导致对某些营养素的需求增加,疾病和药物通常会导致营养素消耗。由于我们社会中发病率和死亡率的增加,这些营养缺乏和不足正在造成巨大的经济成本。综上所述,代谢纠正改善了酶的功能,有利于生理正常功能,从而有助于改善人类的健康和福祉。本文的目的是描述和介绍最佳代谢纠正的概念,作为一种具有成本效益的对抗疾病的功能机制,此外,还有助于疾病的预防和身体的再生和健康。
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[Metabolic correction: a biochemical option against diseases].

Human development and its physiology depends on a number of complex biochemical body processes, many of which are interactive and codependent. The speed and the degree in which many physiological reactions are completed depend on enzyme activity, which in turn depends on the bioavailability of co-factors and micronutrients such as vitamins and minerals. To achieve a healthy physiological state, organism need that biochemical reactions occur in a controlled and specific way at a particular speed and level or grade fully completed. To achieve this, is required an optimal metabolic balance. Factors such as, a particular genetic composition, inadequate dietary consumption patterns, traumas, diseases, toxins and environmental stress all of these factors rising demands for nutrients in order to obtain optimal metabolic balance. Metabolic correction is a biochemical and physiological concept that explains how improvements in cellular biochemistry of an organism can help the body achieve metabolic and physiological optimization. We summarize the contribution of several pioneers in understanding the role of micronutrients in health management. The concept of metabolic correction is becoming a significant term due to the presence of genetic variants that affect the speed of reactions of enzymes, causing metabolic alterations that enhance or promote the state/development of multiple diseases. Decline in the nutritional value of the food we eat, the increase in demand for certain nutrients caused by normal development, diseases and medications induce, usually, nutrients consumption. These nutritional deficiencies and insufficiencies are causing massive economic costs due to increased morbidity and mortality in our society. In summary, metabolic correction improves the enzymatic function, which favors the physiological normal functions, thus, contributing to improving health and the welfare of the human being. The purpose of this paper is to describe and introduce the concept of optimal metabolic correction as a functional cost-effective mechanism against disease, in addition, to contribute to diseases prevention and regeneration of the body and health.

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