Gaba及其受体在癫痫发病中的作用

Q4 Biochemistry, Genetics and Molecular Biology Uspekhi Fiziologicheskikh Nauk Pub Date : 2015-07-01

M N Karpova, L V Kuznetzova, N Yu Klishina

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引用次数: 0

摘要

本文综述了脑gaba能系统的结构和功能组织、gaba能的传递机制、gaba受体的特性和gaba能抑制形式等方面的研究进展。综述了GABA抑制性神经递质和各类GABA受体在癫痫发生中的作用。实验和临床数据证明了GABA及其受体在癫痫发生中的重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Gaba and its Receptors in Pathogenesis of Epilepsy].

This review presents summarizes data on the structural and functional organization of the GABAergic system of the brain, mechanisms of GABAergic transmission, about the characteristics of GABA-receptors and GABAergic inhibition forms. Reviewed issues of involvement of GABA inhibitory neurotransmitter and various types of GABA-receptors in epileptogenesis. The experimental and clinical data testifying to an important role of GABA and its receptors in an epileptogenesis are presented.

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来源期刊

Uspekhi Fiziologicheskikh Nauk Biochemistry, Genetics and Molecular Biology-Physiology

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The journal publishes reviews on various aspects of physiology and also original articles concerned with fundamental problems, based both on the data available in literature and on the experimental results obtained by the contributor.