[一例模仿原发性肺癌的堪萨斯分枝杆菌肺病手术病例]。

Kekkaku : [Tuberculosis] Pub Date : 2015-04-01
Sumitaka Yamanaka, Hiroshi Tomoyasu
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引用次数: 0

摘要

我们报告一个罕见的外科病例,孤立的肺结节,由于结核杆菌堪萨斯。一位59岁的男性因在胸部x光片上偶然发现的左上肺叶异常影而入院检查。胸部ct示结节位于左侧1+2节段,形状不规则,直径35mm。胸部氟-18氟脱氧葡萄糖正电子发射断层扫描显示高代谢性肺病变,最大标准化摄取值为5.1,与肺癌的发现一致。行支气管镜检查以确定肺癌的诊断;但是没有发现恶性细胞。由于我们无法通过支气管镜检查确诊,我们进行了电视胸腔镜手术。术中快速诊断结节为上皮样细胞肉芽肿。切除标本涂片检查抗酸杆菌阳性,分枝杆菌培养阳性,确定为堪萨斯分枝杆菌。手术切除后,对堪萨斯分枝杆菌感染进行抗生素治疗一年。少数肯萨西分枝杆菌感染病例表现为孤立性肺结节。
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[A SURGICAL CASE OF MYCOBACTERIUM KANSASII LUNG DISEASE MIMICKING PRIMARY LUNG CANCER].

We report a rare surgical case of a solitary pulmonary nodule due to Mycobacterium kansasii. A 59-year-old man was admitted to our hospital for examination of an abnormal shadow in the left upper lobe incidentally found on a chest radiogram. Computed tomography of the chest showed that the nodule was located in the left segment 1+2 and was irregularly shaped with a diameter of 35 mm. Thoracic fluorine-18 fluoro-deoxy-glucose positron emission tomography showed a high metabolic pulmonary lesion, with a maximum standardized uptake value of 5.1, consistent with findings for lung cancer. A bronchoscopy was performed to establish the diagnosis of lung cancer; however, it failed to show malignant cells. Because we could not confirm the diagnosis by bronchoscopic examination, video-assisted thoracoscopic surgery was performed. The intraoperative rapid diagnosis of the nodule was epithelioid cell granuloma. Smear test of the resected specimen was positive for acid-fast bacilli, and a culture was also positive for mycobacteria, which were identified as Mycobacterium kansasii. Antibiotic treatment for M. kansasii infection was administered for a year after the surgical resection. Few cases of Mycobacterium kansasii infection present with solitary pulmonary nodules.

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