{"title":"组织修复与再生的最新进展:前景光明。","authors":"Nikolay Ninov, Maximina H Yun","doi":"10.1002/reg2.30","DOIUrl":null,"url":null,"abstract":"<p><p>The fifth EMBO conference on 'The Molecular and Cellular Basis of Regeneration and Repair' took place in the peaceful coastal town of Sant Feliu de Guixols (Spain) on September 2014. The meeting was organised by Emili Saló (U. Barcelona, Spain), Kimberly Mace (U. Manchester, UK), Patrizia Ferretti (University College London, UK) and Michael Brand (Centre for Regenerative Therapies Dresden, Germany) and received the generous support of Society for Developmental Biology, The Company of Biologists, Centre for Regenerative Therapies Dresden, Garland Science and the journals Regeneration and Cell Signalling. The natural surroundings provided an inspiring setting for 185 researchers from all over the world to share their latest findings and views on the field. The conference showcased the great diversity of model organisms used for studying regeneration and tissue repair, including invertebrate and vertebrate species (Fig. 1). Importantly, this diversity in animal models allowed for a global overview of the mechanisms that promote regeneration. In addition, it highlighted some of the unique aspects that confer differences in regenerative capacities among different species. These differences might lie in each of the different steps involved in performing regeneration, including triggering the regenerative response, controlling cellular plasticity, re-stablishing the correct tissue patterns, as well as determining the roles of extrinsic factors, such as the role of inflammation in regeneration. A deeper understanding of these processes in the naturally regenerating species is a prerequisite for advancing the field of regenerative medicine and tissue repair in humans.</p>","PeriodicalId":90316,"journal":{"name":"Regeneration (Oxford, England)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/reg2.30","citationCount":"7","resultStr":"{\"title\":\"Current advances in tissue repair and regeneration: the future is bright.\",\"authors\":\"Nikolay Ninov, Maximina H Yun\",\"doi\":\"10.1002/reg2.30\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The fifth EMBO conference on 'The Molecular and Cellular Basis of Regeneration and Repair' took place in the peaceful coastal town of Sant Feliu de Guixols (Spain) on September 2014. The meeting was organised by Emili Saló (U. Barcelona, Spain), Kimberly Mace (U. Manchester, UK), Patrizia Ferretti (University College London, UK) and Michael Brand (Centre for Regenerative Therapies Dresden, Germany) and received the generous support of Society for Developmental Biology, The Company of Biologists, Centre for Regenerative Therapies Dresden, Garland Science and the journals Regeneration and Cell Signalling. The natural surroundings provided an inspiring setting for 185 researchers from all over the world to share their latest findings and views on the field. The conference showcased the great diversity of model organisms used for studying regeneration and tissue repair, including invertebrate and vertebrate species (Fig. 1). Importantly, this diversity in animal models allowed for a global overview of the mechanisms that promote regeneration. In addition, it highlighted some of the unique aspects that confer differences in regenerative capacities among different species. 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引用次数: 7
摘要
2014年9月,第五届EMBO会议“再生和修复的分子和细胞基础”在宁静的海滨小镇Sant Feliu de Guixols(西班牙)举行。会议由Emili Saló(西班牙巴塞罗那大学)、Kimberly Mace(英国曼彻斯特大学)、Patrizia Ferretti(英国伦敦大学学院)和Michael Brand(德国德累斯顿再生治疗中心)组织,并得到了发育生物学学会、生物学家公司、德累斯顿再生治疗中心、Garland Science和《再生与细胞信号》杂志的慷慨支持。自然环境为来自世界各地的185名研究人员提供了一个鼓舞人心的环境,分享他们在该领域的最新发现和观点。会议展示了用于研究再生和组织修复的模式生物的巨大多样性,包括无脊椎动物和脊椎动物物种(图1)。重要的是,动物模型的这种多样性允许对促进再生的机制进行全球概述。此外,它还强调了不同物种之间再生能力差异的一些独特方面。这些差异可能在于进行再生的每个不同步骤,包括触发再生反应,控制细胞可塑性,重新建立正确的组织模式,以及确定外部因素的作用,例如炎症在再生中的作用。深入了解自然再生物种的这些过程是推进人类再生医学和组织修复领域的先决条件。
Current advances in tissue repair and regeneration: the future is bright.
The fifth EMBO conference on 'The Molecular and Cellular Basis of Regeneration and Repair' took place in the peaceful coastal town of Sant Feliu de Guixols (Spain) on September 2014. The meeting was organised by Emili Saló (U. Barcelona, Spain), Kimberly Mace (U. Manchester, UK), Patrizia Ferretti (University College London, UK) and Michael Brand (Centre for Regenerative Therapies Dresden, Germany) and received the generous support of Society for Developmental Biology, The Company of Biologists, Centre for Regenerative Therapies Dresden, Garland Science and the journals Regeneration and Cell Signalling. The natural surroundings provided an inspiring setting for 185 researchers from all over the world to share their latest findings and views on the field. The conference showcased the great diversity of model organisms used for studying regeneration and tissue repair, including invertebrate and vertebrate species (Fig. 1). Importantly, this diversity in animal models allowed for a global overview of the mechanisms that promote regeneration. In addition, it highlighted some of the unique aspects that confer differences in regenerative capacities among different species. These differences might lie in each of the different steps involved in performing regeneration, including triggering the regenerative response, controlling cellular plasticity, re-stablishing the correct tissue patterns, as well as determining the roles of extrinsic factors, such as the role of inflammation in regeneration. A deeper understanding of these processes in the naturally regenerating species is a prerequisite for advancing the field of regenerative medicine and tissue repair in humans.