使用伽玛探针识别原发性甲状旁腺功能亢进的多腺体疾病。

IF 1.2 International Journal of Endocrine Oncology Pub Date : 2016-02-01 DOI:10.2217/ije.15.27

Kirby Tobin, Rachel R Ayers, Mohammad Rajaei, Rebecca S Sippel, Courtney J Balentine, Dawn Elfenbein, Herb Chen, David F Schneider

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引用次数: 5

摘要

目的:本研究的目的是在放射引导下甲状旁腺切除术中确定阈值伽马探针计数以区分单一腺瘤(SA)和多腺疾病(MGD)。方法:对1656例患者进行回顾性分析。取第一个切除腺体的离体计数并记录为背景计数的百分比。结果:69.4%的MGD患者计数低于50%阈值。50%的阈值正确分组了72.8%的队列。计数超过100%对SA的分类是准确的，计数超过100%的患者中只有6.8%患有MGD。结论:伽玛探头可以帮助外科医生在怀疑MGD时决定继续颈部探查，或在怀疑SA时等待实验室确认治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Use of the gamma probe to identify multigland disease in primary hyperparathyroidism.

Aim: The purpose of this study was to determine threshold gamma probe counts to distinguish single adenoma (SA) from multigland disease (MGD) during radioguided parathyroidectomy.

Methods: A retrospective analysis of 1656 patients was performed. Ex vivo counts of the first excised gland were taken and recorded as a percentage of background counts.

Results: 69.4% of MGD patients had counts below the 50% threshold. The 50% threshold correctly grouped 72.8% of our cohort. Counts of more than 100% were accurate for grouping SA, with only 6.8% of patients with counts more than 100% having MGD.

Conclusions: The gamma probe can aid surgeons in deciding to continue neck exploration if MGD is suspected or wait for labs to confirm cure if SA is suspected.

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来源期刊

International Journal of Endocrine Oncology ONCOLOGY-

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： International Journal of Endocrine Oncology is a quarterly, peer-reviewed journal that helps the clinician to keep up to date with best practice in this fast-moving field. The journal highlights significant advances in basic and translational research, and places them in context for future therapy. The journal presents the latest research findings in diagnosis and management of endocrine cancer, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. The journal welcomes the unsolicited submission of article proposals and original research manuscripts.