细胞外基质膜与结缔组织移植物修复ⅰ/ⅱ类牙龈退缩缺损的比较:裂口研究。

Yogini M, Prabhuji Mlv, Karthikeyan Bv, Sai Jyothsna N
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引用次数: 0

摘要

目的:本研究的目的是评估细胞外基质膜(DynaMatrix®)获得根覆盖的可行性,并将其与结缔组织移植物治疗Miller's I类或II类退行性缺损进行比较。方法:选取10例平均年龄31.2岁的双侧上前磨牙米勒氏ⅰ级或ⅱ级退行缺损患者。每位患者有两个缺陷,随机采用冠状进展皮瓣与结缔组织移植物(CAF+CTG)和冠状进展皮瓣与细胞外膜(DynaMatrix®;CAF + DM)。记录患者术后基线、术后3个月、6个月的临床参数,并对数据进行统计学分析。结果:本研究结果表明,这两种方法是有效的和可预测的根覆盖程序。然而,在减少牙龈萎缩方面,细胞外膜和金标准结缔组织移植物之间没有统计学差异。结论:在本临床研究的范围内,使用胞外膜(DynaMatrix®)可能是结缔组织移植物治疗牙龈退缩的可接受的替代方法。
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Comparison of Extracellular Matrix Membrane and Connective Tissue Graft for Root Coverage in Class I/II Gingival Recession Defects: A Split Mouth Study.

Objective: The aim of this study was to assess the feasibility of extracellular matrix membrane (DynaMatrix®) in obtaining root coverage and compare it to the connective tissue graft for the treatment of Miller's Class I or Class II recession defects.

Methods: Ten patients with a mean age of 31.2 years with bilateral Miller's Class I or Class II recession defects in the upper premolars were recruited. Each patient contributed two defects that were randomly treated by coronally advanced fl ap with connective tissue graft (CAF+CTG) and by coronally advanced flap underlaid with extracellular membrane (DynaMatrix®; CAF+DM). All the clinical parameters were recorded at baseline, three months and six months after surgery and data were statistically analyzed.

Results: The results of this study demonstrated that both the procedures were effective and predictable in root coverage procedures. However, no statistically signifi cant differences in gingival recession reduction were noted between extra cellular membrane and gold standard connective tissue graft.

Conclusion: Within the limits of this clinical study, the use of extracellular membrane (DynaMatrix®) may represent an acceptable alternative to the connective tissue graft for treating gingival recession.

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