难治性心源性休克体外膜氧合的局部网络。

Acute cardiac care Pub Date : 2015-12-01 Epub Date: 2016-06-09 DOI:10.3109/17482941.2016.1174272
Carlotta Sorini Dini, Chiara Lazzeri, Marco Chiostri, Gian Franco Gensini, Serafina Valente
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引用次数: 8

摘要

背景:静脉-动脉体外膜氧合(VA ECMO)是难治性心源性休克(RCS)患者的一种治疗选择。该策略仅限于有能力植入VA ECMO并在此支持下管理患者的有限数量的中心。我们报告了我们的ECMO转诊中心对RCS患者的初步经验。方法:我们回顾性分析了14例接受VA ECMO治疗的RCS患者的ECMO数据登记,这些患者连续入住我们的心脏重症监护病房(ICCU),这是一个ECMO转诊中心。结果:6例患者(6/14,42%)来自外周中心,4例患者直接转至我院重症监护室。住院期间,4例患者因多器官功能衰竭死亡(28.5%),7例患者完全康复,1例患者行心脏移植。其余2例患者因脑出血在等待心脏移植时死亡。30天总死亡率为42.8%,所有幸存者均表现出良好的神经预后。结论:在我们的研究中,经VA ECMO支持的RCS患者生存率高(57%),RCS患者的转移是可行和安全的。我们的数据支持RCS网络需要将患者转移到经验丰富的中心,即使是在ECMO支持下。
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A local network for extracorporeal membrane oxygenation in refractory cardiogenic shock.

Background: Veno-arterial extracorporeal membrane oxygenation (VA ECMO) represents a therapeutic option in patients with refractory cardiogenic shock (RCS). This strategy is limited to a restricted number of centres with capabilities for implanting VA ECMO and management patients on this support. We report on the initial experience of our ECMO referral centre for patients with RCS.

Methods: We retrospectively analysed our ECMO data registry for RCS of 14 patients treated with VA ECMO, consecutively admitted to our intensive cardiac care unit (ICCU), which is an ECMO referral centre.

Results: Six patients (6/14, 42%) came from peripheral centres, four were transferred to our ICCU directly. During ICCU stay, four patients died (28.5%) due to multi-organ failure, seven showed a complete recovery while one underwent cardiac transplantation. The remaining two patients died while waiting for cardiac transplantation because of cerebral haemorrhage. The 30-day overall mortality rate was 42.8%, all survivors showed a good neurologic outcome.

Conclusions: In our series, the survival rate of RCS patients supported by VA ECMO is high (57%) and the transfer of RCS patients is feasible and safe. Our data support that a network for RCS is needed to transfer patients in well experienced centres even on ECMO support.

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