儿童血压和成人心血管疾病的临床前标志物。

IF 3 Q2 Medicine Clinical Medicine Insights-Blood Disorders Pub Date : 2016-05-04 eCollection Date: 2016-01-01 DOI:10.4137/CMBD.S18887
Costan G Magnussen, Kylie J Smith
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引用次数: 31

摘要

成人高血压水平被认为是全球疾病负担最重要的可改变危险因素,尤其是那些心血管(CV)来源的疾病,如中风和缺血性心脏病。由于血压水平从儿童期持续到成年期,儿科血压水平的升高被假设会导致成年期CV负担的增加,因此,可能会在生命过程中提供一个窗口,可以关注原始和初级预防。由于缺乏将儿童血压水平与成人明显的心血管疾病直接联系起来的实质性数据,本综述概述了研究儿童血压与成人心血管疾病临床前标志物之间关系的现有文献。
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Pediatric Blood Pressure and Adult Preclinical Markers of Cardiovascular Disease.

A high blood pressure level in adults is considered the single most important modifiable risk factor for global disease burden, especially those of cardiovascular (CV) origin such as stroke and ischemic heart disease. Because blood pressure levels have been shown to persist from childhood to adulthood, elevations in pediatric levels have been hypothesized to lead to increased CV burden in adulthood and, as such, might provide a window in the life course where primordial and primary prevention could be focused. In the absence of substantive data directly linking childhood blood pressure levels to overt adult CV disease, this review outlines the available literature that examines the association between pediatric blood pressure and adult preclinical markers of CV disease.

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来源期刊
CiteScore
3.70
自引率
0.00%
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审稿时长
8 weeks
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