以家庭为基础的运动干预是否能改善体弱老年人的预后?系统评价的结果。

Reviews in clinical gerontology Pub Date : 2012-02-01 Epub Date: 2012-08-24 DOI:10.1017/S0959259811000165
Andrew P Clegg, Sally E Barber, John B Young, Anne Forster, Steve J Iliffe
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引用次数: 73

摘要

背景:虚弱在老年人中很常见,并且与重要的不良健康结局相关,包括残疾风险增加和长期护理住院。目的:评估以家庭为基础的运动干预是否能改善体弱老年人的预后。资料来源:系统检索随机对照试验(rct)和聚类rct,文献检索截止到2010年2月。研究选择:所有评估以家庭为基础的老年人运动干预的试验均符合条件。主要结果是流动性、生活质量和日常生活活动。次要结局包括长期护理入院和住院。结果:6项rct共987名受试者符合纳入标准。4个试验被认为是高质量的。一项高质量的试验报告了中度但不严重虚弱患者的残疾得到改善。长期护理入院率的荟萃分析确定了风险降低的趋势。其他研究报告了对其他主要和次要结局的不一致影响。结论:有初步证据表明,以家庭为基础的运动干预可以改善中度而不是严重虚弱的老年人的残疾。对于包括生活质量和长期护理入院在内的重要结果的影响存在相当大的不确定性。以家庭为基础的锻炼可能是一种简单、安全且广泛适用的干预措施,可防止体弱老年人的依赖性下降。
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Do home-based exercise interventions improve outcomes for frail older people? Findings from a systematic review.

Background: Frailty is common in older age, and is associated with important adverse health outcomes including increased risk of disability and long-term care admission.

Objectives: To evaluate whether home-based exercise interventions improve outcomes for frail older people.

Data sources: We searched systematically for randomised controlled trials (RCTs) and cluster RCTs, with literature searching to February 2010.

Study selection: All trials that evaluated home-based exercise interventions for frail older people were eligible. Primary outcomes were mobility, quality of life and daily living activities. Secondary outcomes included long-term care admission and hospitalisation.

Results: Six RCTs involving 987 participants met the inclusion criteria. Four trials were considered of high quality. One high quality trial reported improved disability in those with moderate but not severe frailty. Meta-analysis of long-term care admission rates identified a trend towards reduced risk. Inconsistent effects on other primary and secondary outcomes were reported in the other studies.

Conclusions: There is preliminary evidence that home-based exercise interventions may improve disability in older people with moderate, but not severe, frailty. There is considerable uncertainty regarding effects on important outcomes including quality of life and long-term care admission. Home-based exercises are a potentially simple, safe and widely applicable intervention to prevent dependency decline for frail older people.

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