恶性双侧基底额单发纤维性肿瘤。一个病例报告。

IF 0.1 4区 医学 Q4 Medicine Analytical and Quantitative Cytopathology and Histopathology Pub Date : 2016-04-01
Nidhi Mahajan, Kavite Gaur, Shramana Mandal, Ravindra Kumar Saran, Hukum Singh
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引用次数: 0

摘要

背景:孤立性纤维性肿瘤是一种少见的良性间质肿瘤,其特点是累及全身多个部位,在头盖骨内表现罕见。此外,恶性双侧基底额单发纤维性肿瘤极为罕见。虽然不常见,但这种罕见的实体可能包括在成人额叶肿瘤的鉴别诊断中,以确保完全手术切除。该肿瘤属于纤维母细胞增生,与脑膜瘤和血管外皮细胞瘤有密切的形态学重叠,对组织病理学家的诊断提出了挑战。病例:我们报告一例恶性孤立的纤维性肿瘤在双侧基底额区在一个50岁的妇女谁提出间歇性头痛和呕吐和临床放射诊断为脑膜瘤。结论:需要临床放射学和病理学的相关性来识别该肿瘤的侵袭性行为,并帮助临床医生进行适当的手术治疗(完全手术切除)和密切的连续随访。
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Malignant Bilateral Basifrontal Solitary Fibrous Tumor. A Case Report.

Background: Solitary fibrous tumors are rare benign mesenchymal neoplasms characterized by involvement of many sites all over the body with uncommon presentation within the cranium. Furthermore, malignant bilateral basifrontal solitary fibrous tumor is extremely rare. Although uncommon, this rare entity may be included in the differential diagnosis of frontal tumors in adults, to ensure complete surgical resection. The tumor falls under the spectrum of fibroblastic proliferation and shares close morphological overlap with meningiomas and hemangiopericytomas, posing a diagnostic challenge for the histopathologist.

Case: We report a case of a malignant solitary fibrous tumor in the bilateral basifrontal region in a 50-year-old woman who presented with intermittent headache and vomiting and was clinicoradiologically diagnosed with meningioma.

Conclusion: Clinicoradiological and pathological correlation is required for recognizing the aggressive behavior of this tumor and aiding the clinician for appropriate surgical management (complete surgical resection) and close sequential follow-up.

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期刊介绍: AQCH is an Official Periodical of The International Academy of Cytology and the Italian Society of Urologic Pathology.
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