Valentina Villano, Chiara Stella Di Stadio, Antonella Federico, Filomena Altieri, Giuseppina Miselli, Maurizio De Palma, Emilia Rippa, Paolo Arcari
{"title":"人血清胃因子1mrna不是胃癌的信息性生物标志物。","authors":"Valentina Villano, Chiara Stella Di Stadio, Antonella Federico, Filomena Altieri, Giuseppina Miselli, Maurizio De Palma, Emilia Rippa, Paolo Arcari","doi":"10.1186/s12952-016-0057-9","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease.</p><p><strong>Results: </strong>Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals.</p><p><strong>Conclusions: </strong>Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.</p>","PeriodicalId":73849,"journal":{"name":"Journal of negative results in biomedicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12952-016-0057-9","citationCount":"5","resultStr":"{\"title\":\"Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer.\",\"authors\":\"Valentina Villano, Chiara Stella Di Stadio, Antonella Federico, Filomena Altieri, Giuseppina Miselli, Maurizio De Palma, Emilia Rippa, Paolo Arcari\",\"doi\":\"10.1186/s12952-016-0057-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease.</p><p><strong>Results: </strong>Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals.</p><p><strong>Conclusions: </strong>Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.</p>\",\"PeriodicalId\":73849,\"journal\":{\"name\":\"Journal of negative results in biomedicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-07-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1186/s12952-016-0057-9\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of negative results in biomedicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s12952-016-0057-9\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of negative results in biomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s12952-016-0057-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer.
Background: We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease.
Results: Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals.
Conclusions: Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.
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