三种自身免疫性疾病的不寻常关联:乳糜泻,系统性红斑狼疮和桥本甲状腺炎。

Q1 Medicine Auto-Immunity Highlights Pub Date : 2016-12-01 Epub Date: 2016-07-06 DOI:10.1007/s13317-016-0079-9
Viera Boccuti, Antonio Perrone, Alessia D'Introno, Anna Campobasso, Moris Sangineto, Carlo Sabbà
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引用次数: 6

摘要

自身免疫性疾病在女性中更为常见,而且往往相互关联,但在一个患者中出现多种自身免疫性疾病是罕见的。最近,多重自身免疫性综合征的概念被引入来描述至少有三种自身免疫性疾病的患者。我们描述了一个病例的年轻男子与精神症状和乳糜泻(CD)的临床病史,谁被诊断出有其他两种自身免疫性疾病:系统性红斑狼疮(SLE)和桥本甲状腺炎。本病例在不同的模式上是不寻常的:三种自身免疫性疾病的罕见组合,它们在男性中的出现,以及疾病的非典型发病,伴有可能与CD或SLE相关的精神症状。
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An unusual association of three autoimmune disorders: celiac disease, systemic lupus erythematosus and Hashimoto's thyroiditis.

Autoimmune disorders are known to be more frequent in women and often associated each others, but it is rare to see multiple autoimmune diseases in a single patient. Recently, the concept of multiple autoimmune syndrome has been introduced to describe patients with at least three autoimmune diseases. We describe a case of a young man with a clinical history of psychiatric symptoms and celiac disease (CD) who was diagnosed to have other two autoimmune disorders: systemic lupus erythematosus (SLE) and Hashimoto's thyroiditis. This case is unusual upon different patterns: the rare combination of the three autoimmune diseases, their appearance in a man and the atypical onset of the diseases with psychiatric symptoms likely to be related either to CD or to SLE.

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