早期左心室射血分数作为心脏骤停后生存的预测因子。

Acute cardiac care Pub Date : 2016-06-01 Epub Date: 2017-03-22 DOI:10.1080/17482941.2017.1293831
Barry Burstein, Dev Jayaraman, Regina Husa
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引用次数: 9

摘要

背景:心肺复苏和早期除颤已被证明可以改善心脏骤停的结果。停搏后超声心动图的意义,特别是左心室射血分数(LVEF)是未知的。方法:我们对2009年1月1日至2013年12月31日期间发生心脏骤停的患者进行了回顾性队列研究。我们纳入了所有达到自然循环恢复(ROSC),并被三级医疗学术中心的重症监护病房(ICU)或冠状动脉监护病房(CCU)收治的患者。在心脏骤停24小时内接受超声心动图检查的患者纳入分析。主要结局是生存。结果:151例患者达到ROSC,其中97例在24 h内进行了骤停后超声心动图检查,70.8%为男性,平均年龄67.8岁(SD: 15.9)。24 h平均LVEF为35.7 (SD: 17.8)。LVEF > 40%不是30天生存率或出院的预测指标。多变量分析中唯一有意义的预测因子是年龄、休克节律的存在和到ROSC的时间。结论:尽管经常要求超声心动图,但心脏骤停后复苏的患者LVEF大于40%并不是生存的预测指标。
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Early left ventricular ejection fraction as a predictor of survival after cardiac arrest.

Background: Cardiopulmonary resuscitation and early defibrillation have been shown to improve outcomes of cardiac arrest. The significance of the post-arrest echocardiogram, specifically the left ventricular ejection fraction (LVEF) is unknown.

Methods: We performed a retrospective cohort study of patients who suffered from cardiac arrest between 1 January 2009 and 31 December 2013. We included all patients who achieved return of spontaneous circulation (ROSC), and were admitted to the intensive care unit (ICU) or coronary care unit (CCU) of a tertiary care academic center. Patients who underwent echocardiography within 24 h of cardiac arrest were included for analysis. The primary outcome was survival.

Results: We identified 151 patients who achieved ROSC of which 97 underwent post-arrest echocardiogram within 24 h. 70.8% were males and the mean age was 67.8 years (SD: 15.9). The mean LVEF at 24 h was 35.7 (SD: 17.8). LVEF > 40% was not a predictor of survival at 30 days or hospital discharge. The only significant predictors on multivariate analyses were age, presence of shockable rhythm and time to ROSC.

Conclusion: Although echocardiograms are frequently ordered, LVEF greater than 40% in patients who are resuscitated after a cardiac arrest is not a predictor of survival.

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