猪圆环病毒2型及其在撒哈拉以南非洲相关疾病的全球状况

IF 1.1 Q4 VIROLOGY Advances in Virology Pub Date : 2017-01-01 Epub Date: 2017-03-12 DOI:10.1155/2017/6807964
Kayode O Afolabi, Benson C Iweriebor, Anthony I Okoh, Larry C Obi
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引用次数: 41

摘要

在全球范围内,猪圆环病毒2型(PCV2)是一种公认的具有巨大经济价值的养猪业病毒病原体。在欧洲,它是造成断奶后多系统消耗综合征(PMWS)和许多其他疾病综合征(通常被认为是猪圆环病毒相关疾病(PCVAD))严重破坏的主要原因。PCV2感染,特别是PMWS,对世界不同地区的生猪生产造成了巨大的经济损失。它已经在全球不同地区进行了研究和报道,包括:北美和南美、欧洲、亚洲、大洋洲、中东和加勒比地区。然而,迄今为止,在撒哈拉以南非洲地区和整个非洲大陆,对这种病毒及其相关疾病的研究严重不足。49个国家中有两个(仅占目前构成撒哈拉以南非洲的约4%)尽管该病毒无处不在,但对报告病例和病毒病原体发生情况的记录有限。本文综述了猪圆环病毒及其相关疾病在全球猪群中的发现情况,强调了PCV2疫苗和抗病毒药物开发的最新趋势,以及撒哈拉以南非洲国家猪群中这一重要病毒病原体发生情况的信息缺口。这将为该地区利益攸关方立即采取相关行动敲响警钟。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa.

Globally, Porcine circovirus type 2 (PCV2) is a recognized viral pathogen of great economic value in pig farming. It is the major cause of ravaging postweaning multisystemic wasting syndrome (PMWS) and many other disease syndromes generally regarded as Porcine circovirus associated diseases (PCVAD) in Europe. PCV2 infections, specifically PMWS, had impacted huge economic loss on swine production at different regions of the world. It has been studied and reported at different parts of the globe including: North and South America, Europe, Asia, Oceania, Middle East, and the Caribbean. However, till date, this virus and its associated diseases have been grossly understudied in sub-Sahara African region and the entire continent at large. Two out of forty-nine, representing just about 4% of countries that make up sub-Sahara Africa presently, have limited records on reported cases and occurrence of the viral pathogen despite the ubiquitous nature of the virus. This review presents an overview of the discovery of Porcine circovirus and its associated diseases in global pig herds and emphasizes the latest trends in PCV2 vaccines and antiviral drugs development and the information gaps that exist on the occurrence of this important viral pathogen in swine herds of sub-Saharan Africa countries. This will serve as wake-up call for immediate and relevant actions by stakeholders in the region.

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来源期刊
CiteScore
2.30
自引率
0.00%
发文量
23
审稿时长
22 weeks
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