应用关节镜观察柔肝药治疗膝关节骨性关节炎的疗效。

Chong-Hua Dai, Jun Sun, Xin-Feng Gu, Yu-Xin Zheng
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引用次数: 0

摘要

背景:采用关节镜观察肝软化药治疗膝关节骨性关节炎(OA)的临床疗效。材料和方法:40例膝关节OA患者,通过关节镜检查确定其软骨分类为Outerbridge II级、III级或II + III级,随机分配到肝软化药物联合氨基葡萄糖治疗组或单独氨基葡萄糖治疗组。分别于第60、120、180天进行临床观察并测定综合疗效评分。第二次关节镜检查于180天进行。结果:治疗组在不同时间点症状体征均有明显改善。治疗组疗效优于对照组。在第二次关节镜检查中分析软骨时,未观察到进一步的退变。结论:关节镜清创后,肝柔药联合氨基葡萄糖治疗膝关节OA是一种可行有效的解决方案。
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USING ARTHROSCOPY TO OBSERVE THE EFFECT OF LIVER-SOFTENING MEDICINE ON KNEE OSTEOARTHRITIS.

Background: Arthroscopy was used to observe the clinical effect of liver-softening medicine for treating knee osteoarthritis (OA).

Materials and methods: Forty knee OA patients with cartilage classifications of Outerbridge grade II, III, or II plus III determined via arthroscopy were randomly assigned to a treatment of liver-softening medicine plus glucosamine or a control treatment of glucosamine alone. Clinical observation and determination of the comprehensive effect score were performed at 60, 120, and 180 days. A second arthroscopy was performed at 180 days.

Results: Signs and symptoms significantly improved at different time points in the treatment group. The effects in the treatment group were better than those in the control group. When analyzing the cartilage during the second arthroscopy, no further degeneration was observed.

Conclusions: After arthroscopic debridement, the treatment of knee OA with liver-softening medicine in conjunction with glucosamine is a feasible and effective solution.

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