Ismail Dragon Legason, Alex Atiku, Ronald Ssenyonga, Peter Olupot-Olupot, John Banson Barugahare
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Ethical approval was granted.</p><p><strong>Results: </strong>Categorically, the prevalence of anaemia was; 37.2, 33.3 and 11.8% among children aged 1-5 years, 6-11 years and 12-14 years respectively. Overall anaemia prevalence was 34.4%. The risk of anaemia was higher among males than females [(OR = 1.3, 95% CI = 0.8, 2.1), <i>P</i> = .22]. Malaria was associated with a 1.5 times risk of anaemia though not statistically significant in the multivariate analysis (<i>P = .19)</i>. Maternal parity <5 (<i>P</i> = .002), and stunting [(OR = 2.5, 95% CI = 1.3, 4.7), <i>P</i> = .004] were positively associated with anaemia. There was a positive correlation between household size and income (<i>Pearson X</i><sup><i>2</i></sup> <i>= 22.96; P = .001)</i>, implying that large families were of higher socioeconomic status.</p><p><strong>Conclusions: </strong>This study demonstrates that anaemia is more prevalent in the under-5 age. The risk factors are stunting and low maternal parity. Interventions that address nutritional deficiencies in both pre-school and school children are recommended. Malaria and helminthiasis control measures counter the risk of anaemia. Further studies are required to investigate the association between maternal parity and anaemia found in this study.</p>","PeriodicalId":37740,"journal":{"name":"BMC Hematology","volume":" ","pages":"10"},"PeriodicalIF":0.0000,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12878-017-0081-0","citationCount":"38","resultStr":"{\"title\":\"Prevalence of Anaemia and Associated Risk Factors among Children in North-western Uganda: A Cross Sectional Study.\",\"authors\":\"Ismail Dragon Legason, Alex Atiku, Ronald Ssenyonga, Peter Olupot-Olupot, John Banson Barugahare\",\"doi\":\"10.1186/s12878-017-0081-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Despite the public health significance of anaemia in African children, its broader and often preventable risk factors remain largely under described. This study investigated, for the first time, the prevalence of childhood anaemia and its risk factors in an urban setting in Uganda.</p><p><strong>Methods: </strong>A total of 342 children were enrolled. Venous blood samples were collected in EDTA tubes and analyzed using Symex 500i (Symex Corp. Japan). Stool and urine samples were analyzed according to established standard methods. Anthropometric indicators were calculated according to the CDC/WHO 1978 references. Ethical approval was granted.</p><p><strong>Results: </strong>Categorically, the prevalence of anaemia was; 37.2, 33.3 and 11.8% among children aged 1-5 years, 6-11 years and 12-14 years respectively. Overall anaemia prevalence was 34.4%. The risk of anaemia was higher among males than females [(OR = 1.3, 95% CI = 0.8, 2.1), <i>P</i> = .22]. Malaria was associated with a 1.5 times risk of anaemia though not statistically significant in the multivariate analysis (<i>P = .19)</i>. 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引用次数: 38
摘要
背景:尽管非洲儿童贫血具有重要的公共卫生意义,但其更广泛且往往可预防的风险因素在很大程度上仍未得到描述。这项研究首次调查了乌干达城市环境中儿童贫血的患病率及其危险因素。方法:共纳入342名儿童。静脉血样本采集于EDTA管中,使用Symex 500i(日本Symex公司)进行分析。根据建立的标准方法分析粪便和尿液样本。人体测量指标根据CDC/WHO 1978年参考文献计算。伦理批准。结果:从分类上看,贫血患病率为;1-5岁、6-11岁和12-14岁儿童分别占37.2%、33.3%和11.8%。总体贫血患病率为34.4%。男性发生贫血的风险高于女性[(OR = 1.3, 95% CI = 0.8, 2.1), P = 0.22]。疟疾与1.5倍的贫血风险相关,但在多变量分析中没有统计学意义(P = 0.19)。产妇产次P = 0.002)和发育迟缓[(OR = 2.5, 95% CI = 1.3, 4.7), P = 0.004]与贫血呈正相关。家庭规模与收入呈正相关(Pearson X2 = 22.96;P = .001),这意味着大家庭的社会经济地位更高。结论:本研究表明,贫血在5岁以下儿童中更为普遍。危险因素是发育迟缓和产妇胎次低。建议采取干预措施,解决学龄前儿童和学龄儿童的营养缺乏问题。疟疾和寄生虫病控制措施可对抗贫血风险。需要进一步的研究来调查本研究中发现的产妇胎次与贫血之间的关系。
Prevalence of Anaemia and Associated Risk Factors among Children in North-western Uganda: A Cross Sectional Study.
Background: Despite the public health significance of anaemia in African children, its broader and often preventable risk factors remain largely under described. This study investigated, for the first time, the prevalence of childhood anaemia and its risk factors in an urban setting in Uganda.
Methods: A total of 342 children were enrolled. Venous blood samples were collected in EDTA tubes and analyzed using Symex 500i (Symex Corp. Japan). Stool and urine samples were analyzed according to established standard methods. Anthropometric indicators were calculated according to the CDC/WHO 1978 references. Ethical approval was granted.
Results: Categorically, the prevalence of anaemia was; 37.2, 33.3 and 11.8% among children aged 1-5 years, 6-11 years and 12-14 years respectively. Overall anaemia prevalence was 34.4%. The risk of anaemia was higher among males than females [(OR = 1.3, 95% CI = 0.8, 2.1), P = .22]. Malaria was associated with a 1.5 times risk of anaemia though not statistically significant in the multivariate analysis (P = .19). Maternal parity <5 (P = .002), and stunting [(OR = 2.5, 95% CI = 1.3, 4.7), P = .004] were positively associated with anaemia. There was a positive correlation between household size and income (Pearson X2= 22.96; P = .001), implying that large families were of higher socioeconomic status.
Conclusions: This study demonstrates that anaemia is more prevalent in the under-5 age. The risk factors are stunting and low maternal parity. Interventions that address nutritional deficiencies in both pre-school and school children are recommended. Malaria and helminthiasis control measures counter the risk of anaemia. Further studies are required to investigate the association between maternal parity and anaemia found in this study.
期刊介绍:
BMC Hematology is an open access, peer-reviewed journal that considers articles on basic, experimental and clinical research related to hematology. The journal welcomes submissions on non-malignant and malignant hematological diseases, hemostasis and thrombosis, hematopoiesis, stem cells and transplantation.