全身振动运动对杜兴氏肌肉萎缩症患者的耐受性良好:系统综述。

Eloá Moreira-Marconi, Danubia C Sá-Caputo, Carla F Dionello, Eliane O Guedes-Aguiar, Cintia R Sousa-Gonçalves, Danielle S Morel, Laisa L Paineiras-Domingos, Patricia L Souza, Cristiane R Kütter, Rebeca G Costa-Cavalcanti, Glenda Costa, Patricia C Paiva, Claudia Figueiredo, Samuel Brandão-Sobrinho-Neto, Christina Stark, Marianne Unger, Mario Bernardo-Filho
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摘要

背景:杜兴氏肌营养不良症(DMD)是由位于 X 染色体上负责产生肌营养不良蛋白的缺陷基因引起的。DMD 患者的肌肉骨骼系统曾出现过并发症。全身振动运动(WBVE)是一种能改善运动障碍患者肌肉骨骼功能的治疗方法。本研究旨在回顾全身振动运动对 DMD 患者的功能活动度、骨骼和肌肉的影响:搜索了四个数据库。找到了三项符合条件的研究;这三项研究都得出结论,认为使用盲人振动治疗 DMD 患者的临床耐受性良好。这些研究使用了侧交变 WBV 系统,频率为 7 - 24 Hz,振幅为 2 - 4 mm:一项研究表明,在使用 WBV 的最初几天,DMD 患者的肌酸激酶会暂时升高,但其他作者并未发现变化。骨量、肌肉力量或骨标志物均无明显变化。一些患者报告在训练期间主观功能有所改善。解读:结论结论:WBV 似乎是一种对 DMD 患者可行且耐受性良好的锻炼方式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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WHOLE-BODY VIBRATION EXERCISE IS WELL TOLERATED IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY: A SYSTEMATIC REVIEW.

Background: Duchenne muscular dystrophy (DMD) is caused by a defective gene located on the X-chromosome, responsible for the production of the dystrophin protein. Complications in the musculoskeletal system have been previously described in DMD patients. Whole body vibration exercise (WBVE) is a treatment that improves musculoskeletal function in movement disorders. The aim of this study was to review the effects of WBVE on functional mobility, bone and muscle in DMD patients.

Materials and methods: Four databases were searched. Three eligible studies were found; all three conclude the management of DMD patients with WBV was clinically well tolerated. The studies used a side-alternating WBV system, frequencies 7 - 24 Hz; and amplitudes 2 - 4 mm.

Results: A work indicates that a temporary increase in creatine kinase in DMD during the first days of WBV was observed, but other authors did not find changes. No significant changes in bone mass, muscle strength or bone markers. Some patients reported subjective functional improvement during training. Interpretation.

Conclusion: It is concluded that WBV seems to be a feasible and well tolerated exercise modality in DMD patients.

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