类风湿关节炎患者接受生物或非生物DMARDs的常规实验室监测综述。

IF 2.3 Q2 RHEUMATOLOGY International Journal of Rheumatology Pub Date : 2017-01-01 Epub Date: 2017-10-31 DOI:10.1155/2017/9614241
William F C Rigby, Kathy Lampl, Jason M Low, Daniel E Furst
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引用次数: 28

摘要

许多用于治疗类风湿性关节炎(RA)的药物的安全性问题可以通过常规实验室监测早期识别毒性来减轻;然而,目前还没有对不同可用RA疗法的推荐监测指南进行全面审查。这篇综述的目的是总结目前RA患者实验室监测的指南,并提供与每种RA适应症药物相关的实验室异常概况的概述。对类风湿性关节炎患者实验室监测血脂、肝转氨酶、血清肌酐、中性粒细胞计数和血小板计数的频率的建议是根据文献检索已发表的建议和指南以及每种药物的处方信息编制的。根据每种药物的处方信息和文献检索,包括荟萃分析和主要临床试验数据,编制每种药物的实验室异常概况。
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Review of Routine Laboratory Monitoring for Patients with Rheumatoid Arthritis Receiving Biologic or Nonbiologic DMARDs.

Safety concerns associated with many drugs indicated for the treatment of rheumatoid arthritis (RA) can be attenuated by the early identification of toxicity through routine laboratory monitoring; however, a comprehensive review of the recommended monitoring guidelines for the different available RA therapies is currently unavailable. The aim of this review is to summarize the current guidelines for laboratory monitoring in patients with RA and to provide an overview of the laboratory abnormality profiles associated with each drug indicated for RA. Recommendations for the frequency of laboratory monitoring of serum lipids, liver transaminases, serum creatinine, neutrophil counts, and platelet counts in patients with RA were compiled from a literature search for published recommendations and guidelines as well as the prescribing information for each drug. Laboratory abnormality profiles for each drug were compiled from the prescribing information for each drug and a literature search including meta-analyses and primary clinical trials data.

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来源期刊
CiteScore
4.40
自引率
0.00%
发文量
9
审稿时长
24 weeks
期刊最新文献
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