腹内肿块,梗阻性黄疸,嗜酸性粒细胞增多。

Rheumatology and immunology research Pub Date : 2022-07-06 eCollection Date: 2022-06-01 DOI:10.2478/rir-2022-0015
Li Wang, Guizhi Zhang, Wenjie Zheng, Xinping Tian, Mengtao Li, Xiaofeng Zeng, Fengchun Zhang
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引用次数: 1

摘要

嗜酸性肉芽肿病合并多血管炎(EGPA)是一种与嗜酸性粒细胞增多相关的全身性血管炎综合征,最常累及肺、皮肤、心血管、胃肠道、肾脏和周围神经系统(PNS)。我们报告一例48岁的男性表现为梗阻性黄疸引起的腹内肿块,他也有升高的外周嗜酸性粒细胞。肿块的病理特征包括血管炎和嗜酸性粒细胞浸润。最初诊断为EGPA,用糖皮质激素和环磷酰胺治疗。患者在6个月后没有得到完全缓解,然后再次活检证实他患有非霍奇金淋巴瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Intra-abdominal Mass, Obstructive Jaundice, and Eosinophilia.

Eosinophilic granulomatosis with polyangiitis(EGPA) is a systemic vasculitis syndrome associated with eosinophilia, which most commonly involves the lung, skin, cardiovascular, gastrointestinal, renal, and peripheral nervous systems (PNS). We report a case of a 48-year-old man presented as obstructive jaundice caused by intra-abdominal mass, and he also had elevated peripheral eosinophils. The pathological features of the mass included vasculitis and eosinophils infiltration. At first he was diagnosed as EGPA and treated by glucocorticoid and cyclophosphamide. The patient did not get complete response after six months and then the repeat biopsy proved that he had non-Hodgkin's lymphoma.

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