门诊患者甲状腺功能减退的患病率及其与糖尿病的关系。

Mariela Bernal, Eddy Escobar, Carmen E Rodríguez González
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摘要

甲状腺功能减退症是成人中最常见的甲状腺疾病。研究发现,显性甲状腺功能减退在2型糖尿病人群中的患病率高于普通人群,但亚临床甲状腺功能减退与2型糖尿病之间的关系仍存在争议。本研究的目的是估计在门诊接受服务的成年人群中甲状腺功能减退的患病率,并确定甲状腺功能减退与糖尿病之间是否存在关联。从2014年期间在mayagez, P.R.家庭医学中心Policlínica Bella Vista门诊就诊的所有成年患者的数据库中,随机抽取200名受试者,并对医疗记录进行了审查。本组糖尿病患病率为22%,甲状腺功能减退患病率为17%。糖尿病患者甲状腺功能减退的患病率为10/44(22.7%)。非糖尿病患者甲状腺功能减退的患病率为24/156(15.4%)。患病率为1.48 (95% CI: 0.77, 2.85;X2 = 1.31, p = 0.25)。这项横断面研究的结果显示,糖尿病患者甲状腺功能减退的患病率较高,这一趋势无统计学意义,这表明应考虑对糖尿病患者进行甲状腺功能减退筛查。甲状腺功能障碍与糖尿病之间的关系需要更多的研究和更多的患者。
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Prevalence of Hypothyroidism and Its Association with Diabetes Mellitus in Patients of an Ambulatory Clinic.

Hypothyroidism is the most common thyroid disorder in the adult population. Studies have found a higher prevalence of overt hypothyroidism in type 2 diabetic population than in the general population, but the relationship between subclinical hypothyroidism and diabetes mellitus 2 is still controversial. The aim of this study is to estimate the prevalence rate of hypothyroidism in the adult population receiving services in an ambulatory clinic and to determine if there is an association between hypothyroidism and diabetes mellitus. From the database of all adult patients who attended the outpatient clinic at Family Medicine Center Policlínica Bella Vista in Mayagüez, P.R. during 2014, a random sample of 200 subjects was obtained and the medical records were reviewed. The prevalence rate of diabetes mellitus in this group was 22% and the prevalence rate of hypothyroidism was 17%. The prevalence rate of hypothyroidism in diabetic patients was 10/44 (22.7%). The prevalence rate of hypothyroidism in non-diabetic patients was 24/156 (15.4%). The prevalence ratio was 1.48 (95% CI: 0.77, 2.85; X2 = 1.31, p = 0.25). The results of this cross-sectional study showed a non-statistically significant tendency for a higher prevalence of hypothyroidism in diabetic patients, which suggest that screening for hypothyroidism among patients with diabetes should be considered. More studies with more patients are necessary to investigate the association between thyroid dysfunction and diabetic patients.

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