浆液性卵巢癌基因组靶向治疗途径

Journal of nature and science Pub Date : 2017-07-01
Joshua Axelrod, Joe Delaney
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引用次数: 0

摘要

基因组测序技术和相应的肿瘤学出版物已经为许多癌症类型产生了大量公开可用的数据集。虽然这使得新的治疗方法成为可能,并且在一些有限的病例中对该疾病进行终身管理,但浆液性卵巢癌的治疗选择仍然令人沮丧。这篇综述总结了我们对卵巢癌的理解的最新进展,重点是异质性、功能基因组学和可操作的数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Pathways to Genome-targeted Therapies in Serous Ovarian Cancer.

Genome sequencing technologies and corresponding oncology publications have generated enormous publicly available datasets for many cancer types. While this has enabled new treatments, and in some limited cases lifetime management of the disease, the treatment options for serous ovarian cancer remain dismal. This review summarizes recent advances in our understanding of ovarian cancer, with a focus on heterogeneity, functional genomics, and actionable data.

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