所有疑似结肠憩室出血的患者都应进行急诊内镜检查吗?

Clinical Medicine Insights. Gastroenterology Pub Date : 2017-09-06 eCollection Date: 2017-01-01 DOI:10.1177/1179552217728906
Takeshi Uehara, Satohiro Matsumoto, Hiroyuki Miyatani, Hirosato Mashima
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引用次数: 4

摘要

目的:我们试图建立一个评分系统,以促进对结肠憩室出血患者进行急诊内窥镜检查的决策。方法:本研究分析了178例经结肠镜检查诊断为结肠憩室出血的便血患者的资料。根据初次内镜检查时是否识别出出血源,将患者分为两组(识别出出血源组和未识别出出血源组),并根据所获得的结果建立预测出血源成功识别的评分系统。结果:确诊组接受口服抗凝治疗或Charlson合并症指数≥6、血清c反应蛋白水平≥1mg /dL、CT增强显像显示造影剂外渗的患者比例均显著高于未确诊组。多因素分析在增强CT图像上发现造影剂外渗(优势比[OR]: 10.6;95%可信区间[CI]: 2.7-42.2)和抗凝剂的使用(OR: 4.5;95% CI: 1.5-13.5)作为结肠憩室出血患者初次内镜检查成功识别出血源的独立预测因素。在此基础上,我们建立了一个评分系统,该评分系统在初次内镜检查时成功识别出血源的敏感性为80%,特异性为81%。结论:在此,我们提出一个评分系统作为一个有用的工具来确定是否需要急诊内窥镜检查个别疑似结肠憩室出血的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Should Emergency Endoscopy be Performed in All Patients With Suspected Colonic Diverticular Hemorrhage?

Objective: We attempted to develop a scoring system for facilitating decision making regarding the performance of emergency endoscopy in patients with colonic diverticular hemorrhage.

Methods: This study involved analysis of the data of 178 patients who presented with hematochezia and were diagnosed as having colonic diverticular hemorrhage by colonoscopy. The patients were divided into 2 groups depending on whether the bleeding source was identified or not at the initial endoscopy (source-identified and source-not-identified groups), and on the basis of the results obtained, we established a scoring system for predicting successful identification of the bleeding source.

Results: The percentages of patients on oral anticoagulant therapy or with a Charlson comorbidity index of ≥6, serum C-reactive protein level of ≥1 mg/dL, or extravasation of contrast medium visualized on contrast-enhanced computed tomographic (CT) images were all significantly higher in the identified than in the nonidentified group. Multivariate analysis identified extravasation of contrast medium on contrast-enhanced CT images (odds ratio [OR]: 10.6; 95% confidence interval [CI]: 2.7-42.2) and use of anticoagulants (OR: 4.5; 95% CI: 1.5-13.5) as independent predictors of successful identification of the bleeding source at the initial endoscopy in patients with colonic diverticular hemorrhage. On the basis of these results, we established a scoring system, which showed a sensitivity of 80% and specificity of 81% for successful identification of the bleeding source at the initial endoscopy.

Conclusions: Herein, we propose a scoring system as a useful tool for determining whether emergency endoscopy is indicated in individual patients with suspected colonic diverticular hemorrhage.

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Clinical Medicine Insights. Gastroenterology
Clinical Medicine Insights. Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
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