Mark A Sak, Peter J Littrup, Neb Duric, Maeve Mullooly, Mark E Sherman, Gretchen L Gierach
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引用次数: 0
摘要
乳房密度是预测乳腺癌风险的最有力指标之一。乳房密度最高的女性与密度最低的女性相比,罹患癌症的几率要高出 4 到 6 倍。乳房密度一般通过乳房 X 线照相术进行评估,但这种方法有其局限性。磁共振成像和超声波断层扫描是一些可替代的成像模式,可帮助乳房 X 线照相术筛查病人和测量乳房密度。随着对乳腺密度的讨论越来越普遍,了解乳腺密度作为风险标志的优势和局限性将变得更加重要。这篇综述文章讨论了乳腺密度与乳腺癌风险之间的关系,列举了使用多种不同成像方式测量乳腺密度的优点和缺点,并简要讨论了如何将乳腺密度应用于乳腺癌的预防和治疗。
Current and Future Methods for Measuring Breast Density: A Brief Comparative Review.
Breast density is one of the strongest predictors of breast cancer risk. Women with the densest breasts are 4 to 6 times more likely to develop cancer compared with those with the lowest densities. Breast density is generally assessed using mammographic imaging; however, this approach has limitations. Magnetic resonance imaging and ultrasound tomography are some alternative imaging modalities that can aid mammography in patient screening and the measurement of breast density. As breast density becomes more commonly discussed, knowledge of the advantages and limitations of breast density as a marker of risk will become more critical. This review article discusses the relationship between breast density and breast cancer risk, lists the benefits and drawbacks of using multiple different imaging modalities to measure density and briefly discusses how breast density will be applied to aid in breast cancer prevention and treatment.
期刊介绍:
Breast Cancer Management (ISSN: 1758-1923) addresses key issues in disease management by exploring the best patient-centered clinical research and presenting this information both directly, as clinical findings, and in practice-oriented formats of direct relevance in the clinic. The journal also highlights significant advances in basic and translational research, and places them in context for future therapy. Breast Cancer Management provides oncologists and other health professionals with the latest findings and opinions on reducing the burden of this widespread disease. Recent research findings and advances clinical practice in the field are reported and analyzed by international experts. The journal presents this information in clear, accessible formats. All articles are subject to independent review by a minimum of three independent experts. Unsolicited article proposals are welcomed and authors are required to comply fully with the journal’s Disclosure & Conflict of Interest Policy as well as major publishing guidelines, including ICMJE and GPP3. Coverage includes: Diagnosis and imaging, Surgical approaches, Radiotherapy, Systemic therapies, Cancer clinical trials, Genetic aspects of disease, Personalized medicine, Translational research and biomarker studies, Management of psychological distress, Epidemiological studies, Pharmacoeconomics, Evidence-based treatment guidelines.