{"title":"词汇扩展:在队列研究中分析时间变化变量的先决条件。","authors":"Nitika, Sidharth Sekhar Mishra, Pallavi Lohani","doi":"10.3126/nje.v7i2.17974","DOIUrl":null,"url":null,"abstract":"<p><p>In a prospective analytical cohort study or a study involving a longer follow up, changing age of participants influence the relationship between exposure and outcome. Usually age at entry is incorporated in the regression model to adjust for age. However, this fails to fully explain and adjust for changing age. For this Lexis expansion, a concept by Wilhelm Lexis, allows the analyst to expand the observations as per age bands and check for confounding and interaction by changing age. Lexis expansion assumes the rates to be constant within an age band.</p>","PeriodicalId":43600,"journal":{"name":"Nepal Journal of Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3126/nje.v7i2.17974","citationCount":"6","resultStr":"{\"title\":\"Lexis Expansion: a prerequisite for analyzing time changing variables in a cohort study.\",\"authors\":\"Nitika, Sidharth Sekhar Mishra, Pallavi Lohani\",\"doi\":\"10.3126/nje.v7i2.17974\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In a prospective analytical cohort study or a study involving a longer follow up, changing age of participants influence the relationship between exposure and outcome. Usually age at entry is incorporated in the regression model to adjust for age. However, this fails to fully explain and adjust for changing age. For this Lexis expansion, a concept by Wilhelm Lexis, allows the analyst to expand the observations as per age bands and check for confounding and interaction by changing age. Lexis expansion assumes the rates to be constant within an age band.</p>\",\"PeriodicalId\":43600,\"journal\":{\"name\":\"Nepal Journal of Epidemiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2017-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3126/nje.v7i2.17974\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nepal Journal of Epidemiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3126/nje.v7i2.17974\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2017/6/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nepal Journal of Epidemiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3126/nje.v7i2.17974","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/6/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Lexis Expansion: a prerequisite for analyzing time changing variables in a cohort study.
In a prospective analytical cohort study or a study involving a longer follow up, changing age of participants influence the relationship between exposure and outcome. Usually age at entry is incorporated in the regression model to adjust for age. However, this fails to fully explain and adjust for changing age. For this Lexis expansion, a concept by Wilhelm Lexis, allows the analyst to expand the observations as per age bands and check for confounding and interaction by changing age. Lexis expansion assumes the rates to be constant within an age band.
期刊介绍：
The Nepal Journal of Epidemiology is a international journal that encompasses all aspects of epidemiology. The journal encourages communication among those engaged in the research, teaching, and application of epidemiology of both communicable and non-communicable disease, including research into health services and medical care. Also covered are new methods, epidemiological and statistical, for the analysis of data used by those who practise social and preventive medicine. It provides the most up-to-date, original, well designed, well interpreted and significant information source in the multidisciplinary field of epidemiology. We publish manuscripts based on the following sections: 1.Short communications 2.Current research trends 3.Original research 4.Case reports 5.Review articles 6.Letter to editor
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