印度北比哈尔邦蛇咬伤的结局决定因素:一项前瞻性医院研究。

Journal of Venom Research Pub Date : 2017-06-28 eCollection Date: 2017-01-01
Takanungsang Longkumer, Lois J Armstrong, Philip Finny
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引用次数: 0

摘要

比哈尔邦是印度每年因蛇咬伤死亡人数第三多的邦。这项为期一年的前瞻性研究对608次蛇咬伤提供了比哈尔邦关于蛇咬伤不利结果决定因素的第一批数据。任何到达医院的延误都会增加蛇咬伤患者出现不良结果的风险[OR 8.88, CI 2.04-38.8]。在去医院之前去看传统医生是唯一具体的、显著的延迟[OR 3.52, CI 1.26-9.7]。在1.5小时内到达医院可以预防不良结果的发生[OR 0.23, CI 0.052-1.0]。摩托车是最佳的交通方式[OR 0.37, CI 0.12-1.1]。其他危险因素为15岁以下患者[OR 3.79, CI 1.57-9.12]和上肢咬伤[OR 2.47, CI 1.01-6.04]。如果由于无法获得抗蛇毒血清而转诊,中毒患者出现不良结果的风险更高[OR 12.2, CI 1.49-100]。为了挽救生命,必须在蛇咬伤管理中包括减少将患者送往医院延误的措施,同时继续提供抗蛇毒血清和辅助通气。
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Outcome determinants of snakebites in North Bihar, India: a prospective hospital based study.

Bihar is the state with the third largest number of snakebite deaths per year in India. This prospective, one-year study of 608 snakebites provides the first data from Bihar on determinants of unfavourable outcomes in snakebites. Any delay in reaching hospital raised the risk of a snakebite patient for an unfavourable outcome [OR 8.88, CI 2.04-38.8]. Attending a traditional practitioner prior to presenting to the hospital was the only specific, significant delay [OR 3.52, CI 1.26-9.7]. Prevention of unfavourable outcomes occurred by presenting to hospital in less than 1.5 hours [OR 0.23, CI 0.052-1.0]. Motorbike was the best mode of transport [OR 0.37, CI 0.12-1.1]. Other risk factors were patients aged under 15 years [OR 3.79, CI 1.57-9.12] and bites to the upper limb [OR 2.47, CI 1.01-6.04]. Patients who were envenomated had a higher risk of unfavourable outcome, if referred due to antivenom being unavailable [OR 12.2, CI 1.49-100]. To save lives, it is imperative that measures to reduce delays in getting patients to hospital must be included in snakebite management, alongside continued availability of antivenom and assisted ventilation.

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