st段抬高型心肌梗死再灌注延迟时间延长的相关因素

Daisy Abreu , M. Salomé Cabral , Fernando Ribeiro
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引用次数: 5

摘要

背景/目的本文的目的是确定总缺血时间延迟的预测因素,这将是st段抬高型心肌梗死患者改善工作的重点。方法回顾性收集患者的临床资料和直接电话访谈。总缺血时间根据症状出现至血流恢复所经过的时间分为两类,小于6小时和小于6小时。采用Logistic回归分析评估总缺血时间与一系列变量之间的关系。通过ROC曲线评估模型的识别能力、敏感性和特异性。结果128例患者中,男性占74.22%,女性占25.78%。平均年龄约62岁(±13.6岁)。在最终模型中选择了与全缺血相关的六个变量:患者年龄,疼痛强度水平,原发地区,社会经济地位,患者在症状出现时的活动,以及患者从另一家医院转院的事实。结论确定与总缺血时间相关的变量,可以识别患者预后可能较差的情况,并应指导教育工作,同时确定可修改的变量以优化治疗。
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Factors associated with longer delays in reperfusion in ST-segment elevation myocardial infarction

Background/objectives

The goal of this paper is to identify the predictors of delay in total ischemia time that would be the focus of improvement efforts in patients with ST-segment elevation myocardial infarction.

Methods

Data was collected retrospectively through the patient's clinical records and by direct telephone interview.

Total ischemic time was categorized in two classes according to the elapsed time since symptom presentation until restored flow, less than 6 h and 6 h or less. Logistic regression analysis was applied to evaluate the relationship between total ischemic time and a set of variables. Discrimination ability of the model was also assessed, as well as sensitivity and specificity, through ROC curves.

Results

Data from 128 patients, 74.22% males and 25.78% females, were analyzed. The average age was approximately 62 years (± 13.6).

Six variables associated with total ischemia were selected in the final model: the patient age, the level of pain intensity, the region of origin, the socioeconomic status, the activity that the patient was performing at the time of symptoms onset, and the fact that the patient has been transferred from another hospital.

Conclusion

The identification of variables associated with the total ischemia time allows the recognition of patients with possibility of worse prognosis, for which should be directed educational efforts and also the identification of variables that can be modified to optimize the therapy.

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