2型糖尿病病程是足底压力升高的预测因子。

Q3 Medicine Review of Diabetic Studies Pub Date : 2018-01-01 Epub Date: 2018-03-10 DOI:10.1900/RDS.2017.14.372
Brooke Falzon, Cynthia Formosa, Liberato Camilleri, Alfred Gatt
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引用次数: 6

摘要

目的:足底压力升高被认为是糖尿病患者溃疡的重要危险因素。本研究的目的是确定糖尿病持续时间是否会影响无明显合并症或足部病理的患者的足底压力。方法:2型糖尿病患者,但没有已知的可能改变血压峰值的混杂因素,根据年龄、体重和性别进行匹配,并根据糖尿病病程分为3组:1组(1-5年)、2组(6-10年)和3组(11-15年)。足底压力记录采用两步协议在一个自行选择的速度。结果:单因素方差分析(ANOVA)显示,三组在第2 - 4跖趾关节(MPJ)感兴趣区(ROI) (p = 0.012和p = 0.022)和左跟(p = 0.049)下的平均足底压力峰值差异显著。此外,左侧第2 - 4 MPJ ROI下的平均压力-时间积分(p = 0.021)和右侧跟下的平均压力-时间积分(p = 0.048)也有显著差异。回归分析证实,第一组的平均峰值足底压力显著低于第三组(p = 0.005)(第二组没有)。结论:随着糖尿病病程的延长,第2 ~第4 MPJ roi下足底压力峰值明显增高。这些发现表明,临床医生应该更多地使用压力测绘技术作为10年以上糖尿病患者临床管理计划的一部分,即使他们没有并发症或畸形,以保留这一高危人群的肢体功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Duration of Type 2 Diabetes is a Predictor of Elevated Plantar Foot Pressure.

Aims: Elevated plantar pressure is considered a significant risk factor for ulceration in diabetes mellitus. The aim of this study was to determine whether duration of diabetes could affect plantar pressure in patients with no known significant comorbidity or foot pathology.

Methods: Participants with type 2 diabetes, but without known confounding factors that could alter peak pressure, were matched for age, weight, and gender and categorized into 3 groups of diabetes duration: group 1 (1-5 yr), group 2 (6-10 yr), and group 3 (11-15 yr). Plantar pressures were recorded utilizing a two-step protocol at a self-selected speed.

Results: One-way analysis of variance (ANOVA) revealed significant differences in mean peak plantar pressures between the three groups under the 2nd - 4th metatarsophalangeal joint (MPJ) region of interest (ROI) (p = 0.012 and p = 0.022, respectively) and left heel (p = 0.049). Also, a significant difference in mean pressure-time integral under the left 2nd - 4th MPJ ROI (p = 0.021) and right heel (p = 0.048) was observed. Regression analysis confirmed that mean peak plantar pressures in the first group (but not in the second group) were significantly lower than in the third group (p = 0.005).

Conclusions: As the duration of diabetes increased, peak plantar pressure increased significantly under the 2nd - 4th MPJ ROIs. These findings suggest that clinicians should make more use of pressure mapping technology as part of their clinical management plan in patients with diabetes >10 yr, even if they have no complications or deformities, to preserve functional limbs in this high-risk population.

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来源期刊
Review of Diabetic Studies
Review of Diabetic Studies Medicine-Internal Medicine
CiteScore
1.80
自引率
0.00%
发文量
28
期刊介绍: The Review of Diabetic Studies (RDS) is the society"s peer-reviewed journal published quarterly. The purpose of The RDS is to support and encourage research in biomedical diabetes-related science including areas such as endocrinology, immunology, epidemiology, genetics, cell-based research, developmental research, bioengineering and disease management.
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