{"title":"[基于缩写MDRD公式与CKD-EPI方程GFR估算的Kielce地区医院急诊科慢性肾脏疾病患病率比较]。","authors":"Pawel Wróbel, Władysław Sułowicz","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Glomerular filtration\nrate plays a key role in the diagnosis of\nchronic kidney disease (CKD). In everyday\npractice GFR is estimated using\nequations based on serum creatinine.\nCommonly used abbreviated MDRD\nformula is not very precise in patients\nwith mildly impaired renal function,\nunderestimating eGFR when greater\nthan 60 ml/min/1.73 m2. CKD-EPI formula,\nrecommended by KDIGO, might\nbe a good alternative in this situation.\nThe aim of the study was to compare\nthe prevalence of consecutive\nstages of CKD in the group of patients\nfrom Emergency Department having\ncalculated eGFR according MDRD and\nCKD-EPI formulas</p><p><strong>Materials and methods: </strong>The retrospective\nstudy was performed in the\ngroup of 1,452 patients (762 women\nand 690 men aged 57.4 years ± 19.8\nyears). Estimated GFR (eGFR) was calculated\nbased on MDRD and CKD-EPI\nformulas and the obtained results were\nanalyzed according patients location in\nthe consecutive group of CKD, used\nformulas, sex and age.</p><p><strong>Results: </strong>The mean values of eGFR\nfor both formulas were similar and for\nMDRD was 68.6 ± 22.3 ml/min/ 1.73 m2\nwhile for CKD-EPI 69.18 ± 24.4 ml/\nmin/1.73 m2. The highest differences\nwere observed in the early stages of\nCKD where the calculation of eGFR\nbased on CKD-EPI vs MDRD formula\ngives an increase of population in\nstage G1 of CKD by 5.7% (342 vs 241\npersons) and reduction by 7.8% (625\nvs 737) in the stage G2.</p><p><strong>Conclusions: </strong>Both formulas have\nthe similar value in the estimation\nof CKD. The differences concerning\nmainly G1 and G2 stages.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Comparison of the prevalence of chronic kidney disease in patients of the Emergency Department of the Regional Hospital in Kielce based on GFR estimation according abbreviated MDRD formula or CKD-EPI equation].\",\"authors\":\"Pawel Wróbel, Władysław Sułowicz\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Glomerular filtration\\nrate plays a key role in the diagnosis of\\nchronic kidney disease (CKD). In everyday\\npractice GFR is estimated using\\nequations based on serum creatinine.\\nCommonly used abbreviated MDRD\\nformula is not very precise in patients\\nwith mildly impaired renal function,\\nunderestimating eGFR when greater\\nthan 60 ml/min/1.73 m2. CKD-EPI formula,\\nrecommended by KDIGO, might\\nbe a good alternative in this situation.\\nThe aim of the study was to compare\\nthe prevalence of consecutive\\nstages of CKD in the group of patients\\nfrom Emergency Department having\\ncalculated eGFR according MDRD and\\nCKD-EPI formulas</p><p><strong>Materials and methods: </strong>The retrospective\\nstudy was performed in the\\ngroup of 1,452 patients (762 women\\nand 690 men aged 57.4 years ± 19.8\\nyears). Estimated GFR (eGFR) was calculated\\nbased on MDRD and CKD-EPI\\nformulas and the obtained results were\\nanalyzed according patients location in\\nthe consecutive group of CKD, used\\nformulas, sex and age.</p><p><strong>Results: </strong>The mean values of eGFR\\nfor both formulas were similar and for\\nMDRD was 68.6 ± 22.3 ml/min/ 1.73 m2\\nwhile for CKD-EPI 69.18 ± 24.4 ml/\\nmin/1.73 m2. The highest differences\\nwere observed in the early stages of\\nCKD where the calculation of eGFR\\nbased on CKD-EPI vs MDRD formula\\ngives an increase of population in\\nstage G1 of CKD by 5.7% (342 vs 241\\npersons) and reduction by 7.8% (625\\nvs 737) in the stage G2.</p><p><strong>Conclusions: </strong>Both formulas have\\nthe similar value in the estimation\\nof CKD. The differences concerning\\nmainly G1 and G2 stages.</p>\",\"PeriodicalId\":21148,\"journal\":{\"name\":\"Przeglad lekarski\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Przeglad lekarski\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Przeglad lekarski","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Comparison of the prevalence of chronic kidney disease in patients of the Emergency Department of the Regional Hospital in Kielce based on GFR estimation according abbreviated MDRD formula or CKD-EPI equation].
Introduction: Glomerular filtration
rate plays a key role in the diagnosis of
chronic kidney disease (CKD). In everyday
practice GFR is estimated using
equations based on serum creatinine.
Commonly used abbreviated MDRD
formula is not very precise in patients
with mildly impaired renal function,
underestimating eGFR when greater
than 60 ml/min/1.73 m2. CKD-EPI formula,
recommended by KDIGO, might
be a good alternative in this situation.
The aim of the study was to compare
the prevalence of consecutive
stages of CKD in the group of patients
from Emergency Department having
calculated eGFR according MDRD and
CKD-EPI formulas
Materials and methods: The retrospective
study was performed in the
group of 1,452 patients (762 women
and 690 men aged 57.4 years ± 19.8
years). Estimated GFR (eGFR) was calculated
based on MDRD and CKD-EPI
formulas and the obtained results were
analyzed according patients location in
the consecutive group of CKD, used
formulas, sex and age.
Results: The mean values of eGFR
for both formulas were similar and for
MDRD was 68.6 ± 22.3 ml/min/ 1.73 m2
while for CKD-EPI 69.18 ± 24.4 ml/
min/1.73 m2. The highest differences
were observed in the early stages of
CKD where the calculation of eGFR
based on CKD-EPI vs MDRD formula
gives an increase of population in
stage G1 of CKD by 5.7% (342 vs 241
persons) and reduction by 7.8% (625
vs 737) in the stage G2.
Conclusions: Both formulas have
the similar value in the estimation
of CKD. The differences concerning
mainly G1 and G2 stages.
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