埃塞俄比亚奥罗米亚比绍图总医院急性腹泻病治疗中抗生素使用模式评估

Advances in Medicine Pub Date : 2018-05-02 eCollection Date: 2018-01-01 DOI:10.1155/2018/2376825
Selamawit Tulu, Tarekegne Tadesse, Addisu Alemayehu Gube
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引用次数: 12

摘要

背景:大多数急性腹泻病是自限性的,不需要常规治疗。经验性抗微生物药物治疗仅推荐用于痢疾和侵袭性细菌性腹泻。在世界各地的临床实践中,不合理使用抗生素治疗急性腹泻是很常见的。开展这项研究是为了评估埃塞俄比亚东谢瓦Bishoftu总医院治疗急性腹泻病的抗生素使用模式。方法与材料:以单位为基础的横断面研究于2016年4月1日至4月30日进行。回顾性收集2015年1月至2015年12月腹泻病患者的数据,采用结构化问卷,输入SPSS (IBM 20)进行描述性统计。结果:303例患者中,男性占51.2%,女性占48.8%。其中,62%是5岁以下的儿童。263例(86.8%)患者使用8种不同类型的抗生素,其中复方新诺明(178例,58.7%)是使用最多的抗生素,其次是环丙沙星(33例,10.9%)和阿莫西林(14例,4.6%)。根据粪便中有血,14.5%的病例为侵袭性细菌型。根据世界卫生组织的建议,抗生素的过度使用率为72.3%。结论:本研究表明,在Bishoftu总医院急性腹泻的成人和5岁以下儿童中,抗生素的过度使用都很高。复方新诺明是最常用的抗生素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Assessment of Antibiotic Utilization Pattern in Treatment of Acute Diarrhoea Diseases in Bishoftu General Hospital, Oromia Ethiopia.

Background: Majority of acute diarrhoeal diseases are self-limiting and do not require routine treatment. Treatment with empirical antimicrobials is recommended only for dysenteric and invasive bacterial diarrhoea. Irrational use of antibiotics in treatment of acute diarrhoea is common in clinical practice worldwide. This study was carried out to assess the pattern of antibiotic use for acute diarrhoeal diseases in Bishoftu General Hospital, East Shewa Ethiopia.

Methods and materials: Institution based cross-sectional study was conducted from April 1 to April 30, 2016. Data were collected retrospectively from patients treated for diarrhoeal diseases from January 2015 to December 2015 using structured questionnaires and entered into SPSS (IBM 20) and descriptive statistics was carried out.

Results: Among the 303 patients, 51.2% were males and 48.8% were females. Of them, 62% were children under five years. Two hundred sixty three (86.8%) patients received eight different types of antibiotics and cotrimoxazole (178 patients, 58.7%) was the most prescribed antibiotics, followed by ciprofloxacin (33, 10.9%) and amoxicillin (14, 4.6%). Based on the presence of blood in stools, 14.5% of cases were of invasive bacterial type. According to the recommendations of WHO, the rate of overuse of antibiotics was 72.3%.

Conclusion: This study revealed that there was high overuse of antibiotics for both adults and children under five with acute diarrhoea in Bishoftu General Hospital. And Cotrimoxazole was the most prescribed antibiotic.

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