不典型病程的老年乳糜泻患者水肿和贫血综合征鉴别诊断的困难。

I A Viktorova, I A Grishechkina, L N Sobol, T N Polomoshnova
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引用次数: 0

摘要

目的:分析老年不典型乳糜泻诊断的复杂性。本文对63岁的不典型乳糜泻患者进行了临床观察,主要表现为水肿和贫血综合征。麦胶蛋白抗体、组织转谷氨酰胺酶抗体高滴度,小肠黏膜组织学改变(Marsh II),存在DQA1*0501等位基因均确诊。在严格的无麸质饮食的背景下,我已经持续半年的临床缓解,血清指标正常化。结论:将伴有水肿和贫血综合征的乳糜泻患者纳入诊断筛查计划,可以建立正确的诊断并降低该患者并发症(包括恶性肿瘤)的风险。
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THE DIFFICULTIES OF DIFFERENTIAL DIAGNOSIS OF EDEMATOUS AND ANEMIC SYNDROMES IN AN EDERLY PATIENT WITH ATYPICAL COURSE OF COELIAC DISEASE.

Objective: Analysis of the complexities of diagnosis of atypical celiac disease in elderly patients.

Key points: A clinical observation of the patient 63 years with atypical form of celiac disease, have flowed mainly from edematous and anemic syndrome. High titers of antibodies to gliadin, tissue transglutaminase, histological changes of the mucous membrane of the small intestine (Marsh II), the presence DQA1*0501 of the alleles have confirmed diagnosis. Against the background of strict gluten-free diet and a half years I have come persistent clinical remission with normalization of serum indicators.

Conclusion: Inclusion in the plan of diagnostic screening for celiac disease in patients \'vith edematous and anemic syndrome possible to establish the correct diagnosis and to reduce the risk of complications (including malignancies) in this patient.

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