脓毒性皮肤栓塞显示肺炎克雷伯菌肝脓肿综合征的严重病例。

JMM case reports Pub Date : 2018-04-12 eCollection Date: 2018-05-01 DOI:10.1099/jmmcr.0.005148
Florentina Paraschiv, Gabriel Adrian Popescu, Alina Maria Borcan
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引用次数: 2

摘要

简介:肺炎克雷伯菌肝脓肿综合征(KLAS)的特征是由肺炎克雷伯菌高毒力菌株引起的菌血症、肝脓肿和转移性感染,通常属于荚膜血清型K1或K2。最初,在东亚描述了KLAS;最近在世界不同地区报告了孤立病例。病例介绍:我们描述了一例女性KLAS包括脑膜,眼部和皮肤转移性感染和器官功能障碍(凝血异常,血小板减少症和肌酐水平升高)。从其中一个皮肤栓子中培养出肺炎克雷伯菌的高黏液粘稠度菌株,随后通过血培养证实。患者经脓肿引流及长期抗生素治疗后完全恢复。结论:我们指出了对每个脓毒性病灶进行采样的重要性,以确定传播性感染的病因。
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Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome.

Introduction: Klebsiella pneumoniae liver abscess syndrome (KLAS) is characterized by bacteraemia, liver abscesses and metastatic infection caused by a hypervirulent strain of Klebsiella pneumoniae, usually belonging to the capsular serotype K1 or K2. Initially, KLAS was described in Eastern Asia; recently isolated cases have been reported from different parts of the world.

Case presentation: We describe the case of a woman with KLAS including meningeal, ocular and cutaneous metastatic infection and organ dysfunctions (coagulation abnormalities, thrombocytopenia and increased creatinine level). The identification of a hypermucoviscous strain of Klebsiella pneumoniae was possible by culture from one of the cutaneous emboli and subsequently confirmed by blood cultures. The patient fully recovered after abscess drainage and prolonged antibiotic treatment.

Conclusion: We have pointed out about the importance of sampling each septic focus in order to identify the aetiology of a disseminate infection.

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