Adnan I Qureshi, Muhammad A Saleem, Nishath Naseem, Shawn S Wallery
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The EQ-5D VAS score was obtained by subject's indication of his/her health state on a scale of 0 (worst) to 100 (best).</p><p><strong>Results: </strong>Angioplasty and/or stent placement was performed in 10 patients for stenosis in extracranial vertebral (<i>n</i> = 6), intracranial vertebral (<i>n</i> = 1), subclavian (<i>n</i> = 2), or innominate artery (<i>n</i> = 1). There was a significant reduction in preprocedure severity [mean ± standard deviation (SD)] of stenosis compared with postprocedure severity (79.9 ± 14.05% vs. 26.4 ± 37.7%, <i>p</i> < 0.001). There was a significant improvement in mean values of EQ-5D VAS postprocedure compared with preprocedure values (72 vs. 57.5, <i>p</i> = 0.018). Minimal important difference (improvement of at least 0.074) on EQ-5D utility index and on VAS (improvement ≥ 10 points) was reported by five and six of 10 patients, respectively.</p><p><strong>Conclusions: </strong>Improvement in QOL appears to be an important measure of effectiveness of ET in patients with vertebral, subclavian, or innominate arterial stenosis with recurrent episodes of vertigo, near syncope, and/or ataxia.</p>","PeriodicalId":88555,"journal":{"name":"Journal of vascular and interventional neurology","volume":"10 1","pages":"7-13"},"PeriodicalIF":0.0000,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999308/pdf/jvin-10-1-2.pdf","citationCount":"0","resultStr":"{\"title\":\"Effect of Endovascular Treatment on Quality of Life in Patients with Recurrent Symptoms Associated with Vertebral, Subclavian, or Innominate Arterial Stenosis.\",\"authors\":\"Adnan I Qureshi, Muhammad A Saleem, Nishath Naseem, Shawn S Wallery\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Patients with vertebral, subclavian, or innominate arterial stenosis can present with recurrent symptoms that can adversely affect the quality of life (QOL). We aimed at determining the short-term effects of endovascular treatment (ET) on QOL in these patients.</p><p><strong>Methods: </strong>European Quality of Life Five Dimension Scale (EQ-5D) utility index and visual analog scale (VAS) were ascertained before and within one month of ET in patients with vertebral, subclavian, or innominate arterial stenosis with recurrent episodes of vertigo, near syncope, and/or ataxia. The EQ-5D utility scores were derived from responses to five questions on EQ-5D questionnaire (-0.109 for the least to 1 for most favorable). The EQ-5D VAS score was obtained by subject's indication of his/her health state on a scale of 0 (worst) to 100 (best).</p><p><strong>Results: </strong>Angioplasty and/or stent placement was performed in 10 patients for stenosis in extracranial vertebral (<i>n</i> = 6), intracranial vertebral (<i>n</i> = 1), subclavian (<i>n</i> = 2), or innominate artery (<i>n</i> = 1). There was a significant reduction in preprocedure severity [mean ± standard deviation (SD)] of stenosis compared with postprocedure severity (79.9 ± 14.05% vs. 26.4 ± 37.7%, <i>p</i> < 0.001). There was a significant improvement in mean values of EQ-5D VAS postprocedure compared with preprocedure values (72 vs. 57.5, <i>p</i> = 0.018). Minimal important difference (improvement of at least 0.074) on EQ-5D utility index and on VAS (improvement ≥ 10 points) was reported by five and six of 10 patients, respectively.</p><p><strong>Conclusions: </strong>Improvement in QOL appears to be an important measure of effectiveness of ET in patients with vertebral, subclavian, or innominate arterial stenosis with recurrent episodes of vertigo, near syncope, and/or ataxia.</p>\",\"PeriodicalId\":88555,\"journal\":{\"name\":\"Journal of vascular and interventional neurology\",\"volume\":\"10 1\",\"pages\":\"7-13\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999308/pdf/jvin-10-1-2.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of vascular and interventional neurology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of vascular and interventional neurology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景:椎动脉、锁骨下动脉或腹内动脉狭窄患者会出现反复发作的症状,对生活质量(QOL)产生不利影响。我们旨在确定血管内治疗(ET)对这些患者生活质量的短期影响:方法:我们在椎动脉、锁骨下动脉或腹内动脉狭窄并伴有反复发作的眩晕、近晕厥和/或共济失调的患者接受 ET 前和 ET 后一个月内确定了欧洲生活质量五维量表(EQ-5D)效用指数和视觉模拟量表(VAS)。EQ-5D 实用性评分是根据对 EQ-5D 问卷中五个问题的回答得出的(-0.109 为最不利,1 为最有利)。EQ-5D VAS评分由受试者以0(最差)至100(最佳)的标准来表示其健康状况:结果:10 名患者因颅内椎动脉(6 例)、颅内椎动脉(1 例)、锁骨下动脉(2 例)或腹内动脉(1 例)狭窄而接受了血管成形术和/或支架置入术。手术前狭窄严重程度[平均值 ± 标准差 (SD)]与手术后严重程度相比有明显降低(79.9 ± 14.05% vs. 26.4 ± 37.7%,P < 0.001)。与术前相比,术后 EQ-5D VAS 平均值有明显改善(72 vs. 57.5,p = 0.018)。10名患者中分别有5人和6人报告了EQ-5D效用指数和VAS的最小重要差异(改善至少0.074)(改善≥10分):结论:对于反复发作眩晕、近晕厥和/或共济失调的椎动脉、锁骨下动脉或腹内动脉狭窄患者,改善 QOL 似乎是衡量 ET 疗效的重要指标。
Effect of Endovascular Treatment on Quality of Life in Patients with Recurrent Symptoms Associated with Vertebral, Subclavian, or Innominate Arterial Stenosis.
Background: Patients with vertebral, subclavian, or innominate arterial stenosis can present with recurrent symptoms that can adversely affect the quality of life (QOL). We aimed at determining the short-term effects of endovascular treatment (ET) on QOL in these patients.
Methods: European Quality of Life Five Dimension Scale (EQ-5D) utility index and visual analog scale (VAS) were ascertained before and within one month of ET in patients with vertebral, subclavian, or innominate arterial stenosis with recurrent episodes of vertigo, near syncope, and/or ataxia. The EQ-5D utility scores were derived from responses to five questions on EQ-5D questionnaire (-0.109 for the least to 1 for most favorable). The EQ-5D VAS score was obtained by subject's indication of his/her health state on a scale of 0 (worst) to 100 (best).
Results: Angioplasty and/or stent placement was performed in 10 patients for stenosis in extracranial vertebral (n = 6), intracranial vertebral (n = 1), subclavian (n = 2), or innominate artery (n = 1). There was a significant reduction in preprocedure severity [mean ± standard deviation (SD)] of stenosis compared with postprocedure severity (79.9 ± 14.05% vs. 26.4 ± 37.7%, p < 0.001). There was a significant improvement in mean values of EQ-5D VAS postprocedure compared with preprocedure values (72 vs. 57.5, p = 0.018). Minimal important difference (improvement of at least 0.074) on EQ-5D utility index and on VAS (improvement ≥ 10 points) was reported by five and six of 10 patients, respectively.
Conclusions: Improvement in QOL appears to be an important measure of effectiveness of ET in patients with vertebral, subclavian, or innominate arterial stenosis with recurrent episodes of vertigo, near syncope, and/or ataxia.