关于银纳米颗粒在牙科生物材料中的应用和结合的当前观点。

Clujul medical (1957) Pub Date : 2018-07-01 Epub Date: 2018-07-31 DOI:10.15386/cjmed-935
Mihai Flaviu Şuhani, Grigore Băciuţ, Mihaela Băciuţ, Raluca Şuhani, Simion Bran
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引用次数: 39

摘要

引言:纳米技术的关键思想是通过开发原子和分子来构建和保存功能结构。纳米技术已被证明在药理学、组织工程、临床诊断、低温状态下生物组织的长期保存、蛋白质检测、肿瘤破坏和磁共振成像方面至关重要。本文的目的是综述有关纳米结构材料的特殊特性、应用及其在牙科中的优势的文献。方法:采用PubMed、Cochrane和Medline进行电子科学数据库研究。使用了以下关键词:纳米技术、纳米牙科和银纳米颗粒。最初,从上述国际数据库中检索到1650篇原创文章,并对其进行了详细筛选。我们包括了关于纳米结构颗粒和银纳米颗粒在当代牙科所有领域的综合应用的文献综述。病例报告、临床试验、社论和意见书在我们研究的第一阶段被排除在外。52篇文章符合所有筛选标准,最终被筛选和审查。结果:纳米技术涉及各种类型的纳米材料的生产,在生物医学领域具有潜在的应用。银纳米颗粒有能力消除产生龋齿的细菌或修复有蛀牙迹象的牙釉质。纳米牙科将通过使用纳米结构材料来改善口腔健康。纳米技术在当代牙科中提供的治疗机会包括局部麻醉、牙科超敏反应的永久治疗、正畸和使用纳米机器人洁牙剂的口腔保健。结论:我们综述的研究主要支持纳米技术和纳米结构材料,强调了它们的质量和对牙科领域的增强作用。尽管许多受益于银纳米颗粒特性的产品仍然昂贵且具有排他性,但我们可以预见,在不久的将来,将纳米颗粒纳入牙科生物材料的需求将得到重大改进。
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Current perspectives regarding the application and incorporation of silver nanoparticles into dental biomaterials.

Introduction: The key idea of nanotechnology is to construct and preserve functional structures by means of exploiting atoms and molecules. Nanotechnology has proven to be crucial in pharmacological medicine, tissue engineering, clinical diagnosis, long term conservation of biological tissues in a cryogenic state, protein detection, tumor destruction and magnetic resonance imaging.The aim of this paper is to review the literature on the specific characteristics of nanostructured materials, their applications and advantages that they bring to dentistry.

Method: We conducted an electronic scientific database research that included PubMed, Cochrane and Medline. The following keywords were used: nanotechnology, nanodentistry and silver nanoparticles. Initially 1650 original articles were retrieved from the these mentioned international databases, which were screened in detail. We included literature reviews that dealt with the comprehensive applications of nanostructured particles and silver nanoparticles in particular, in all fields of contemporary dentistry. Case reports, clinical trials, editorials and opinion letters were excluded in the first phase of our research. Fifty two articles met all the selection criteria and were ultimately selected and reviewed.

Results: Nanotechnology deals with the production of various types of nanomaterials with potential applications in the field of biomedicine. Silver nanoparticles have the capacity to eliminate dental caries producing bacteria or repair teeth enamel with signs of dental decay. Nanodentistry will allow better oral health by use of nanostructured materials. Treatment opportunities that nanotechnology has to offer in contemporary dentistry include local anesthesia, permanent treatment of dental hypersensitivity, orthodontic and oral health care with nanorobotic dentifrice.

Conclusion: The studies that we reviewed are largely in favor of nanotechnology and nanostructured materials, highlighting their qualities and enhancements they bring to the field of dentistry. Although many of these products that benefit from silver nanoparticles properties are still expensive and exclusive, we can foresee major improvements and demand regarding dental biomaterials with nanoparticles incorporated in the near future.

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