[前哨淋巴结活检和腋窝清扫]。

Nihon Geka Gakkai zasshi Pub Date : 2016-11-01
Masato Takahashi
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引用次数: 0

摘要

William Stewart Halsted医生首先主张将乳房全切除术合并胸肌切除和腋窝淋巴结清扫作为乳腺癌的标准手术。前哨淋巴结活检的有效性在100年后得到证实。当前哨淋巴结活检显示淋巴结内没有癌细胞时,标准方法是省略腋窝清扫。近年来,有一些关于前哨淋巴结活检呈转移阳性时省略腋窝清扫的有效性的报道。当前哨淋巴结存在微转移时,可以忽略腋窝清扫。然而,当存在大转移时,有必要参照Z0011研究的纳入标准来确定是否应省略腋窝清扫。腋窝淋巴结清扫的并发症可能包括上臂水肿、肩关节移位障碍和神经病变。早期康复治疗方案可维持肩关节活动。良好的卫生条件,包括指甲,使用保湿剂,以及在受伤时尽早使用抗炎药,可以预防淋巴水肿。如果出现淋巴水肿,佩戴弹性绷带或袖,手工淋巴引流,并在合格教练的指导下进行运动机能学练习是有效的。
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[SENTINEL LYMPH NODE BIOPSY AND AXILLARY DISSECTION].

Dr. William Stewart Halsted first advocated performing total mastectomy with pectoral muscle resection and axillary lymph node dissection as the standard surgery for breast cancer. The effectiveness of the sentinel lymph node biopsy was confirmed 100 years later. When a sentinel lymph node biopsy shows no cancer cells in the lymph node, the standard method is to omit axillary dissection. In recent years, there have been some reports of the validity of omitting axillary dissection when sentinel lymph node biopsy is positive for metastasis. When micrometastasis is present in sentinel lymph nodes, it is reasonable to omit axillary dissection. However, when macrometastasis is present, it is necessary to determine whether axillary dissection should be omitted by referring to the inclusion criteria of the Z0011 study. Complications of axillary lymph node dissection may include upper arm edema, glenohumeral joint excursion obstacles, and neuropathy. Early rehabilitation regimens can maintain glenohumeral joint excursion. Good sanitation including the nails, the use of moisturizers, and early administration of antiinflammatory agents for injuries can prevent lymphedema. If lymphedema develops, the wearing of an elastic bandage or sleeve, manual lymph drainage, and kinesiology exercises with a qualified instructor are effective.

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