2015年亚太地区原发性肝癌专家会议(APPLE)精选摘要。

IF 1.2 Q4 ONCOLOGY Hepatic Oncology Pub Date : 2016-01-01 Epub Date: 2015-11-30 DOI:10.2217/hep.15.37
Augusto Villanueva
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引用次数: 0

摘要

肝癌目前在全球癌症相关死亡率中排名第二;由于晚期患者的治疗选择有限,这仍然是一个日益严重的健康问题。迄今为止,在索拉非尼之后测试分子疗法的所有III期临床试验都失败了,并且仍然没有一个验证的癌基因成瘾循环。尽管目前面临着巨大的挑战,但近年来取得了显著的进展。亚太原发性肝癌专家会议(APPLE)旨在促进国际和地区专家在肝癌研究和管理方面的科学交流。多年来,它已巩固为亚太地区的临床医生和研究人员提供肝癌不同方面的全面更新的主要资源。参加这些会议的人数非常多,每次会议平均有1000人参加。正如预测的那样,2015年版提供了对该疾病的临床管理和分子发病机制的最新发展的杰出概述。
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Selected summary for the 2015 Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE).

Liver cancer is now ranked second in terms of cancer-related mortality worldwide; with limited treatment options for patients at advanced stages it remains a growing health problem. All Phase III clinical trials testing molecular therapies after sorafenib have so far failed, and there is still not a validated oncogene addiction loop. Despite the present huge challenges, advancements in the recent years have been remarkable. The Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE) was designed to promote scientific exchanges of international and regional experts in the study and management of liver cancer. Over the years it has consolidated as a major resource to provide a thorough update to clinicians and researchers located in the Asia-Pacific region in different aspects of liver cancer. Attendance at these meetings is exceptional, with an average of 1000 attendees at each conference. As predicted, the 2015 edition provided an outstanding overview of the latest developments in the clinical management and molecular pathogenesis of the disease.

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来源期刊
Hepatic Oncology
Hepatic Oncology ONCOLOGY-
CiteScore
0.40
自引率
0.00%
发文量
4
审稿时长
13 weeks
期刊介绍: Primary liver cancer is the sixth most common cancer in the world, and the third most common cause of death from malignant disease. Traditionally more common in developing countries, hepatocellular carcinoma is becoming increasingly prevalent in the Western world, primarily due to an increase in hepatitis C virus infection. Emerging risk factors, such as non-alcoholic fatty liver disease and obesity are also of concern for the future. In addition, metastatic tumors of the liver are more common than primary disease. Some studies report hepatic metastases in as many as 40 to 50% of adult patients with extrahepatic primary tumors. Hepatic Oncology publishes original research studies and reviews addressing preventive, diagnostic and therapeutic approaches to all types of cancer of the liver, in both the adult and pediatric populations. The journal also highlights significant advances in basic and translational research, and places them in context for future therapy. Hepatic Oncology provides a forum to report and debate all aspects of cancer of the liver and bile ducts. The journal publishes original research studies, full reviews and commentaries, with all articles subject to independent review by a minimum of three independent experts. Unsolicited article proposals are welcomed and authors are required to comply fully with the journal''s Disclosure & Conflict of Interest Policy as well as major publishing guidelines, including ICMJE and GPP3.
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Treatment journey of patients with hepatocellular carcinoma using real-world data in British Columbia, Canada. The predictive value of liver tests for the presence of liver metastases. Hepatic arterial infusion chemotherapy with or without lenvatinib for unresectable cholangiocarcinoma: a single-center retrospective study. Clinical outcomes by Child-Pugh Class in patients with advanced hepatocellular carcinoma in a community oncology setting. Management of hepatocellular carcinoma from diagnosis in routine clinical practice.
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