[胆囊切除术后膀胱括约肌功能障碍的鉴别治疗]。

M V Repin, V Yu Mikryukov
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引用次数: 0

摘要

目的:探讨胆囊切除术后疑似Oddi括约肌功能障碍患者的鉴别治疗方法。材料与方法:169例胆囊切除术后患者分为两组。第一组- 60例患者经多次手术后组成对照组。他们对临床、实验室和超声数据进行了多变量分析,揭示了器质性胆汁淤积的最显著迹象,并以分数表示。第二组109例疑似Oddi括约肌功能障碍患者,无器质性病理症状。采用肝胆闪烁显像(GBSG)评估胆汁流出类型。在诊断有疑点的病例中,可进行磁共振胆管造影和/或逆行胆管造影。结果:根据评分系统,第一组患者得分在4分及以上(8,7±3,87)分。仅7例(11.6%)患者行GBSG,所有病例均检测到胆汁淤积型流出。第二组的估计点数为2 ~ 3分(2,43±0,34;P < 0.05)。所有患者均行GBSG检查,显示三种类型的胆汁流出:21例正常(19.2%),8例胆汁淤积(7.3%),80例加速(73.3%)。当细化诊断10例(9%)患者有隐藏的胆汁流出器质性疾病时,作为手术指征。结论:采用评分系统对疑似Oddi括约肌功能障碍进行评估,便于区分患者进行有创性研究和手术治疗。在我们研究组109例得分低于4分的患者中,他们以功能障碍为主,但详细检查结果显示,9%的患者有潜在的器质性改变,已成为手术治疗的指征。
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[DIFFERENTIAL MANAGEMENT AT THE SPHINCTER OF ODDI DYSFUNCTION AFTER CHOLECYSTECTOMY].

Aim: Develop a differential management at the patients with suspected sphincter of Oddi dysfunction after cholecystectomy.

Materials and methods: 169 patients after cholecystectomy, divided into 2 groups. 1st group - 60 patients after repeated surgery formed as a comparison group. They multivariate analysis of clinical, laboratory and ultrasonic data revealed the most significant signs of organic causes of cholestasis, expressed in scores. 2nd group - 109 patients with a suspected sphincter of Oddi dysfunction, who did not have symptoms of organic pathology. Types of bile outflow were assessed by hepatobiliary scintigraphy (GBSG). In cases of doubtful diagnoses computer tomography, magnetic resonance cholangiopancreatography, and/or retrograde cholangiopancreatography are performed.

Results: According to the scoring system, patients 1st group scored 4 or more (8,7 ± 3,87) points. GBSG performed only in 7 (11.6%) patients, and in all cases the cholestatic type of bile outflow was detected. The amount of estimated points in the 2nd group was 2-3 points (2,43 ± 0,34; p < 0.05). GBSG performed in all patients and three types of bile outflow were revealed: normal - in 21 (19.2%) patients, cholestatic in 8 (7.3%), and accelerated - in 80 (73.3%) patients. When refining the diagnosis in 10 (9%) patients had hidden organic disorders of bile outflow, served as an indication for surgery.

Conclusion: Scoring system for the assessment of the suspected sphincter of Oddi dysfunction allows to differentiate of patients for invasive research and surgery. In our study group of 109 patients received less than 4 points, they have dominated the functional disorders, but the results of a detailed examination, 9% of patients had latent organic changes that have become indications for surgical treatment.

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