老年髋部骨折手术后不良事件发生的时间:美国外科医师学会国家手术质量改进计划19873例患者的研究

Daniel D Bohl, Andre M Samuel, Matthew L Webb, Adam M Lukasiewicz, Nathaniel T Ondeck, Bryce A Basques, Nidharshan S Anandasivam, Jonathan N Grauer
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引用次数: 13

摘要

本研究采用前瞻性手术登记来描述老年髋部骨折手术后10个术后不良事件的发生时间。作为美国外科医师学会国家手术质量改进计划(ACS-NSQIP)的一部分,共有19,873名年龄≥70岁的髋部骨折患者接受了手术。心肌梗死的术后中位诊断天数(和四分位数范围)为3天(1-5),心脏骤停需要心肺复苏3天(0-8),中风3天(1-10),肺炎4天(2-10),肺栓塞4天(2-11),尿路感染7天(2-13),深静脉血栓形成9天(4-16),脓毒症9天(4-18),死亡11天(6-19),手术部位感染16天(11-22)。对于最早诊断的不良事件,不良事件发生率在术后第30天减少。对于后期诊断的不良事件,不良事件发生率在术后第30天仍然很高。研究结果有助于实现更有针对性的临床监测,为患者提供咨询,并确定有效研究特定不良事件所需的随访时间。在风险最大的时间段内,骨科医生应该对每个不良事件进行最低阈值的检测。
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Timing of Adverse Events Following Geriatric Hip Fracture Surgery: A Study of 19,873 Patients in the American College of Surgeons National Surgical Quality Improvement Program.

This study uses a prospective surgical registry to characterize the timing of 10 postoperative adverse events following geriatric hip fracture surgery. There were 19,873 patients identified who were ≥70 years undergoing surgery for hip fracture as part of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP). The median postoperative day of diagnosis (and interquartile range) for myocardial infarction was 3 (1-5), cardiac arrest requiring cardiopulmonary resuscitation 3 (0-8), stroke 3 (1-10), pneumonia 4 (2-10), pulmonary embolism 4 (2-11), urinary tract infection 7 (2-13), deep vein thrombosis 9 (4-16), sepsis 9 (4-18), mortality 11 (6-19), and surgical site infection 16 (11-22). For the earliest diagnosed adverse events, the rate of adverse events had diminished by postoperative day 30. For the later diagnosed adverse events, the rate of adverse events remained high at postoperative day 30. Findings help to enable more targeted clinical surveillance, inform patient counseling, and determine the duration of follow-up required to study specific adverse events effectively. Orthopedic surgeons should have the lowest threshold for testing for each adverse event during the time period of greatest risk.

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