混杂的危险因素和预防措施驱动肾结石的全球构成。

Samuel Shin, Aneil Srivastava, Nazira A Alli, Bidhan C Bandyopadhyay
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引用次数: 19

摘要

在发达国家和发展中国家,肾结石正在以惊人的速度增加。随着肾结石疾病的全球激增,确定影响肾结石当前全球格局的风险因素至关重要。我们这篇综述的目的是:识别和分析导致全球范围内结石形成的四类风险因素:生活方式、遗传、饮食和环境;并探讨肾结石形成的预防措施。我们还通过已发表的科学文献(即PubMed®)进行了数据搜索,发现生活方式和肥胖与钙结石病例之间存在显著联系。利用联合国粮食及农业组织和世界卫生组织的饮食摄入和肥胖因素指标以及气候数据,建立了肾结石风险的预计总风险世界地图模型。由于医学和人口统计信息来源有限,对全球肾结石的全面分析几乎是不可能的,但我们希望这篇综述可以进一步阐明全球肾结石分析的混杂危险因素和预防措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Confounding risk factors and preventative measures driving nephrolithiasis global makeup.

Nephrolithiasis is increasing in developed and developing countries at an alarming rate. With the global spike in kidney stone diseases, it is crucial to determine what risk factors are influencing the current global landscape for kidney stones. Our aims for this review are: to identity and analyze the four categories of risk factors in contributing to the global scale of stone formation: lifestyle, genetics, diet, and environment; and discuss preventative measures for kidney stone formation. We also performed data search through the published scientific literature, i.e., PubMed® and found that there is a significant link between lifestyle and obesity with cases of calcium stones. Food and Agriculture Organization of the United Nations and World Health Organization factor indicators for dietary intake and obesity, along with climate data were used to create the projected total risk world map model for nephrolithiasis risk. Complete global analyses of nephrolithiasis deplete of generalizations is nearly insurmountable due to limited sources of medical and demographic information, but we hope this review can provide further elucidation into confounding risk factors and preventative measures for global nephrolithiasis analysis.

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