葡萄牙北部人群中认知障碍和痴呆症的患病率和原因。

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-02-01 Epub Date: 2018-12-04 DOI:10.1177/1533317518813550

Luis Ruano, Natália Araújo, Mariana Branco, Rui Barreto, Sandra Moreira, Ricardo Pais, Vítor Tedim Cruz, Nuno Lunet, Henrique Barros

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引用次数: 0

摘要

背景：血管疾病可能是葡萄牙等中风高发国家痴呆症流行病学的重要因素：在葡萄牙等中风高发国家，血管疾病可能在痴呆症的流行病学中扮演重要角色：评估葡萄牙人群队列中认知障碍的患病率和病因：方法：使用迷你精神状态检查和蒙特利尔认知评估对 EPIPorto 队列中年龄≥55 岁的个体（n = 730）进行评估。对得分低于年龄/教育调整临界点的人进行进一步评估，以确定痴呆症或轻度认知障碍（MCI），并确定其最常见的原因：结果：共发现 36 例 MCI/痴呆症病例，MCI 调整后患病率为 4.1%，痴呆症调整后患病率为 1.3%。MCI/痴呆症最常见的病因是血管性疾病（52.8%），其次是阿尔茨海默病（36.1%）：这些发现凸显了血管性认知障碍在葡萄牙痴呆症流行病学中的重要性，并就其预防和管理提出了重要的公共卫生信息，可能会推广到其他中风负担较重的国家。

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Prevalence and Causes of Cognitive Impairment and Dementia in a Population-Based Cohort From Northern Portugal.

Background: Vascular disease may play an important role in the epidemiology of dementia in countries with high stroke incidence, such as Portugal.

Objective: To assess the prevalence and etiology of cognitive impairment in a population-based cohort from Portugal.

Methods: Individuals ≥55 years (n = 730) from the EPIPorto cohort were assessed using the Mini-Mental State Examination and the Montreal Cognitive Assessment. Those scoring below the age-/education-adjusted cutoff points were further evaluated to identify dementia or mild cognitive impairment (MCI) and to define its most common causes.

Results: Thirty-six cases of MCI/dementia were identified, corresponding to adjusted prevalences of 4.1% for MCI and 1.3% for dementia. The most common cause of MCI/dementia was vascular (52.8%), followed by Alzheimer's disease (36.1%).

Conclusion: These findings highlight the importance of vascular cognitive impairment in the epidemiology of dementia in Portugal and carry an important public health message regarding its prevention and management, possibly extending to other countries with a high-stroke burden.

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来源期刊

American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY

CiteScore

5.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).