行为变异型额颞叶痴呆症患者自杀风险高。

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-06-01 Epub Date: 2018-12-17 DOI:10.1177/1533317518817609

Milena Zucca, Elisa Rubino, Alessandro Vacca, Flora Govone, Annalisa Gai, Paola De Martino, Silvia Boschi, Salvatore Gentile, Maria Teresa Giordana, Innocenzo Rainero

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引用次数: 0

摘要

目的：本研究旨在确定行为变异型额颞叶痴呆症（bvFTD）患者自杀意念和自杀未遂的发生率，并评估可能的自杀风险因素：采用自杀意念量表（SSI）对35名bvFTD患者和25名对照组患者的自杀风险进行评估：根据 SSI，40% 的 bvFTD 患者有自杀意念，而对照组的这一比例仅为 8% ( P = .009)。有 4 名 bvFTD 患者曾试图自杀，而对照组中没有（P = .006）。有自杀风险的 bvFTD 患者的焦虑、抑郁、压力和绝望程度高于无自杀风险的患者（P < .001）。与仅有自杀意念的患者相比，企图自杀的患者更年轻，病程更长。耐人寻味的是，40%的帕金森病患者表现出高度的自杀意念：我们的研究结果表明，bvFTD 患者的自杀风险很高。我们的研究结果表明，bvFTD 患者有很高的自杀风险。

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High Risk of Suicide in Behavioral Variant Frontotemporal Dementia.

Aim: The purpose of the study was to determine the prevalence of suicidal ideation and attempts in patients with behavioral variant frontotemporal dementia (bvFTD), evaluating possible risk factors for suicidality.

Methods: Risk of suicide was assessed using the Scale for Suicide Ideation (SSI) in 35 patients with bvFTD and 25 controls.

Results: According to SSI, 40% of patients with bvFTD had suicidal ideation in comparison to 8% of controls ( P = .009). Four patients with bvFTD have attempted suicide versus none control ( P = .006). Patients with bvFTD with suicide risk showed higher levels of anxiety, depression, stress, and hopelessness than patients without suicide risk ( P < .001). Patients who attempted suicide were younger and had a longer disease duration than those with only suicide ideation. Intriguingly, 40% of patients with parkinsonism presented high level of suicide ideation.

Conclusions: Our findings show that patients with bvFTD have a high risk of suicide. Additional studies in larger populations are needed to confirm our results.

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来源期刊

American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY

CiteScore

5.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).