ABCD3-I评分较高的TIA患者颅内狭窄、不稳定颈动脉斑块和多血管受累的发生率较高。

Q2 Medicine Functional neurology Pub Date : 2018-10-01
Q Yu, W Miao, J Han
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引用次数: 0

摘要

ABCD3-I标准已被证明在常规临床实践中有效地用于辅助短暂性脑缺血发作(TIA)风险分层和治疗。在这项前瞻性研究中,我们旨在探讨90例TIA患者的风险分层与动脉狭窄位置、颈动脉斑块形态和血管累及之间的关系,并通过ABCD3-I评分对风险进行分层。记录临床变量如总胆固醇、甘油三酯、低密度脂蛋白胆固醇、糖化血红蛋白、同型半胱氨酸和高敏c反应蛋白水平。在7天的随访中,终点是随后的中风。90例患者根据ABCD3-I评分分为3个危险组。结果显示,ABCD3-I评分越高的患者颅内狭窄发生率越高(P < 0.05),颈动脉斑块组织越少(P < 0.05),多支血管受累性越低(P < 0.05)。
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TIA patients with higher ABCD3-I scores are prone to a higher incidence of intracranial stenosis, unstable carotid plaques and multiple-vessel involvement.

The ABCD3-I criteria have proved to be effective for use in regular clinical practice to assist in transient ischemic attack (TIA) risk stratification and treatment. In this prospective study we aimed to explore the relationships between risk stratification and arterial stenosis location, carotid plaque morphology and vessel involvement in 90 TIA patients, stratifying risk by ABCD3-I scores. Clinical variables such as total cholesterol, triglyceride, low-density lipoprotein cholesterol, glycosylated hemoglobin, homocysteine and high-sensitive C-reactive protein levels were recorded. The endpoint was subsequent stroke at seven-day follow-up. Ninety patients were divided into three risk groups on the basis of their ABCD3-I scores. The results revealed that patients with higher ABCD3-I scores showed a higher occurrence of intracranial stenosis (P < 0.05), less organized carotid plaques (P < 0.05) and multiple-vessel involvement (P < 0.05).

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来源期刊
Functional neurology
Functional neurology 医学-神经科学
CiteScore
3.90
自引率
0.00%
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0
审稿时长
>12 weeks
期刊介绍: Information not localized
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