导管相关性尿路感染的谱和抗生素耐药性。

Béla Köves, András Magyar, Peter Tenke
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引用次数: 23

摘要

导尿管相关尿路感染(CAUTIs)是最常见的医院感染之一,也是与留置导尿管相关的最常见并发症之一。大多数导管相关感染源于患者自身的会阴菌群,但导管的存在也增加了医院细菌交叉传播的机会。大多数短期导尿管相关菌尿是无症状的,由单一生物体引起,而长期导尿管会促进多种细菌感染和定植。随着导管插入术持续时间的延长,由于在导管表面形成生物膜,细菌尿被认为是普遍存在的。慢性留置导管是不同多重耐药革兰氏阴性菌的重要宿主,因此它们经常与CAUTI分离。不建议治疗导管相关的无症状菌尿,因为这只会促进耐药生物的出现,而不能有效清除导管患者的尿液。
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Spectrum and antibiotic resistance of catheter-associated urinary tract infections.

Catheter associated urinary tract infections (CAUTIs) are amongst the most common nosocomial infections and are also considered among the most common complications associated with indwelling urinary catheters. Most catheter associated infections are derived from the patient's own perineal flora, however the presence of a catheter increases the chance of being colonised by cross transmission of nosocomial bacteria as well. Most episodes of short-term catheter-associated bacteriuria are asymptomatic and are caused by single organisms, while long-term catheterisation promotes multibacterial infections and colonization. With prolonged duration of catheterization bacteriuria is considered universal because of the formation of biofilms on the surface of the catheter. Chronic indwelling catheters are an important reservoir of different multiresistant gram-negative organisms, therefore they are frequently isolated from CAUTIs. Treatment of catheter associated asymptomatic bacteriuria is not recommended because it will only promote the emergence of resistant organisms without effectively clearing the urine of catheterised patients.

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