3岁儿童误服拉莫三嗪致癫痫。

Case Reports in Emergency Medicine Pub Date : 2019-01-13 eCollection Date: 2019-01-01 DOI:10.1155/2019/2675931
Ashley Griswold, Briana Tully, Kenneth Katz, Gillian Beauchamp, Matthew Cook, Robert Cannon
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引用次数: 4

摘要

拉莫三嗪是新一代抗癫痫药物,可阻断钠通道,过量可引起明显的毒性。一个三岁的孩子谁遭受癫痫发作和需要气管插管后意外摄入拉莫三嗪的情况下提出。拉莫三嗪的浓度为23.2微克/毫升,这是儿童意外接触后报告的最高浓度。关于小儿拉莫三嗪中毒的文献综述也包括在内。
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Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion.

Lamotrigine is a new generation antiepileptic which blocks sodium channels and can cause significant toxicity in overdose. A case of a three-year-old child who suffered a seizure and required endotracheal intubation after accidental lamotrigine ingestion is presented. The lamotrigine concentration measured 23.2 mcg/mL which is the highest reported after accidental pediatric exposure. A review of the literature regarding pediatric lamotrigine poisoning is also included.

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