肾移植前透析方式的选择:重要吗?

Deepika Jain, Danny B Haddad, Narender Goel
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引用次数: 41

摘要

终末期肾病(ESRD)患者的数量正在增加,延长了等待肾移植的名单。大多数患者不能及时接受肾移植,尽管肾脏移植后患者的生存和生活质量比透析要好得多。大量希望进行肾脏移植的患者最终都需要某种形式的透析治疗。在美国,大多数ESRD患者选择血液透析(HD)而不是腹膜透析(PD)作为移植前透析方式的选择,尽管研究表明PD是比HD更好的选择。由于各种原因,PD在美国基本上没有得到充分利用。作为决策过程的一部分,患者经常被告知透析方式的选择如何适合他们的生活,但它不清楚,也不经常讨论,它如何影响未来最终的肾移植。在这篇文章中,我们想讨论ESRD的人口统计和结果,透析方式和肾移植相关事件。我们总结了比较PD和HD作为透析方式的数据及其对肾移植后同种异体移植和受体预后的影响。
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Choice of dialysis modality prior to kidney transplantation: Does it matter?

The population of patients with end stage renal disease (ESRD) is increasing, lengthening waiting lists for kidney transplantation. Majority of the patients are not able to receive a kidney transplant in timely manner even though it is well established that patient survival and quality of life after kidney transplantation is far better when compared to being on dialysis. A large number of patients who desire a kidney transplant ultimately end up needing some form of dialysis therapy. Most of incident ESRD patients choose hemodialysis (HD) over peritoneal dialysis (PD) as the modality of choice in the United States, even though studies have favored PD as a better choice of pre-transplant dialysis modality than HD. PD is largely underutilized in the United States due to variety of reasons. As a part of the decision making process, patients are often educated how the choice regarding modality of dialysis would fit into their life but it is not clear and not usually discussed, how it can affect eventual kidney transplantation in the future. In this article we would like to discuss ESRD demographics and outcomes, modality of dialysis and kidney transplant related events. We have summarized the data comparing PD and HD as the modality of dialysis and its impact on allograft and recipient outcomes after kidney transplantation.

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