肝移植患者的严重皮肤念珠菌病。

IF 0.3 Q4 TRANSPLANTATION International Journal of Organ Transplantation Medicine Pub Date : 2019-01-01 Epub Date: 2019-02-01
P Badiee, H Jafarian, S A Malek-Hosseini, F Ghasemmi
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引用次数: 0

摘要

念珠菌感染是免疫功能低下患者的常见病。一名患有肝移植、皮肤坏死、黄疸、呼吸困难和腹水的19岁男孩被送入伊朗南部设拉子的Namazi医院。要求对皮肤病变进行真菌学检查。皮肤样品在沙伯罗德葡萄糖琼脂上培养,并通过直接显微镜涂片进行评价。采用RFLP-PCR对分离酵母进行鉴定。直接涂片观察到假菌丝、囊胚和酵母菌。从培养基中分离到念珠菌,经分子鉴定为白色念珠菌。他在接受任何治疗前就去世了。在免疫功能低下的人群中,皮肤损伤可能是全身性真菌感染的唯一迹象。因此建议仔细注意和跟进。
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Severe Cutaneous Candidiasis in a Liver Transplant Patient.

Candida infections are common diseases in immunocompromised patients. A 19-year-old boy with liver transplantation, necrotic skin lesion, jaundice, dyspnea, and ascites was admitted to Namazi Hospital, Shiraz, southern Iran. The mycological examination for the skin lesion was requested. The skin sample was cultured on Sabouraud dextrose agar and evaluated by direct microscopic smear. Identification of isolated yeast was performed with RFLP-PCR. In direct smear, pseudohyphae, blastopores and yeasts were observed. Candida species was isolated from the media and identified as Candida albicans by molecular method. He died before starting any treatments. A skin lesion may present as the only sign of a systemic fungal infection in immunocompromised people. Careful attention and follow up are therefore recommended.

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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: The International Journal of Organ Transplantation Medicine (IJOTM) is a quarterly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research on transplantation. The scope of the journal includes organ and tissue donation, procurement and preservation; surgical techniques, innovations, and novelties in all aspects of transplantation; genomics and immunobiology; immunosuppressive drugs and pharmacology relevant to transplantation; graft survival and prevention of graft dysfunction and failure; clinical trials and population analyses in the field of transplantation; transplant complications; cell and tissue transplantation; infection; post-transplant malignancies; sociological and ethical issues and xenotransplantation.
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