类风湿性关节炎患者的药物依从性和应对策略:一项横断面研究。

IF 2.3 Q2 RHEUMATOLOGY International Journal of Rheumatology Pub Date : 2019-03-04 eCollection Date: 2019-01-01 DOI:10.1155/2019/4709645
Carolin Berner, Ludwig Erlacher, Karl H Fenzl, Thomas E Dorner
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引用次数: 22

摘要

目的:本研究的目的是确定应对疾病的策略、人口统计学因素和临床因素是否与类风湿关节炎(RA)患者的药物依从性有关。方法:本横断面研究在维也纳风湿病门诊对类风湿性关节炎患者进行。使用药物依从性报告量表评估药物依从性。采用弗莱堡疾病应对问卷对疾病应对策略进行评估。结果:纳入研究的120例患者中有一半(N= 63,52.5%)被认为是完全服药的。女性(优势比[OR]: 4.57, 95%可信区间[CI]: 1.14 - 18.42),年龄较大(54-65岁vs. 65岁vs. 10岁OR= 3.53, CI= 1.04-11.95;1-4年vs >10年OR=3.71, CI= 1.02-13.52)与较高的药物依从性相关。积极应对水平(15.57 vs. 13.47, p=0.01)或转移和自我鼓励水平(16.10 vs. 14.37, p=0.04)在坚持者中显著高于不坚持者。然而,在多元回归模型中,应对策略与依从性无显著相关。结论:年龄、性别、月净收入和疾病持续时间与RA患者药物不依从风险增加相关。在单变量模型中,积极应对、转移和自我鼓励等应对策略与依从性相关,但在调整人口统计学和临床因素后则不相关。
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Medication Adherence and Coping Strategies in Patients with Rheumatoid Arthritis: A Cross-Sectional Study.

Objectives: The aim of this study was to determine if strategies for coping with illnesses, demographic factors, and clinical factors were associated with medication adherence among patients with rheumatoid arthritis (RA).

Methods: This cross-sectional study was conducted at a Viennese rheumatology outpatient clinic on RA patients. Medication adherence was assessed using the Medication Adherence Report Scale. Strategies for coping with illness were assessed using the Freiburg Questionnaire for Coping with Illness.

Results: Half (N=63, 52.5%) of the 120 patients included in the study were considered completely medication adherent. Female sex (odds ratio [OR]: 4.57, 95% confidence interval [CI]: 1.14 - 18.42), older age (54-65 yr vs. <45 yr OR: 9.2, CI:2.0-40.70; >65 yr vs. <45 yr OR 6.93, CI:1,17 - 40.87), middle average income (middle average income vs. lowest income class OR= 0.06, CI= 0.01-0.43), and shorter disease duration (5-10 yr vs. >10 yr OR= 3.53, CI= 1.04-11.95; 1-4 yr vs. >10 yr OR=3.71, CI= 1.02-13.52) were associated with higher medication adherence. Levels of active coping (15.57 vs. 13.47, p=0.01) or diversion and self-encouragement (16.10 vs. 14.37, p=0.04) were significantly higher among adherent as opposed to less adherent participants. However, in multivariate regression models, coping strategies were not significantly associated with adherence.

Conclusions: Age, sex, monthly net income, and disease duration were found to be associated with an increased risk for medication nonadherence among patients with RA. Coping strategies such as active coping, diversion, and self-encouragement were associated with adherence in univariate models, but not when adjusted for demographic and clinical factors.

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来源期刊
CiteScore
4.40
自引率
0.00%
发文量
9
审稿时长
24 weeks
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