茶和咖啡在胃食管反流病发病过程中的作用。

Tao-Yang Wei, Pang-Hsin Hsueh, Shu-Hui Wen, Chien-Lin Chen, Chia-Chi Wang
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引用次数: 0

摘要

目的:胃食管反流病(GERD)的发病率呈上升趋势,该病与饮食习惯密切相关。本研究旨在探讨饮茶和咖啡在胃食管反流病发病中的作用:本研究对在健康体检期间接受上消化道内窥镜检查的人进行了前瞻性研究。每位受试者都填写了反流病问卷(RDQ)。饮用咖啡或茶的定义是连续 3 个月每周至少 4 天饮用该饮料。大量饮用咖啡或茶的定义是每天至少饮用两杯:最终分析共纳入了 1 837 名参与者(970 名男性;年龄为 51.57 ± 10.21 岁),他们都有临床特征和饮用咖啡或茶的数据,无论是否含有牛奶或糖等添加剂。其中,467 人(25.4%)根据 RDQ 评分被诊断为有症状的胃食管反流病,427 人(23.2%)在内镜检查中患有侵蚀性食管炎(EE)。在单变量和多变量分析中,喝咖啡或茶与反流症状或 EE 无关。相反,在单变量分析中,喝加奶咖啡与反流症状有关,喝 "茶和咖啡 "与 EE 有关。然而,在进行多变量分析后,这些相关性变得不明显:结论:喝咖啡或茶并加奶或糖与反流症状或 EE 无关。
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The role of tea and coffee in the development of gastroesophageal reflux disease.

Objective: The incidence of gastroesophageal reflux disease (GERD) is increasing, and the disease has a close association with dietary habits. This study aims to investigate the role of tea and coffee drinking in the development of GERD.

Materials and methods: This study prospectively enrolled individuals who underwent an upper gastrointestinal endoscopy during a health checkup. Each participant completed the reflux disease questionnaire (RDQ). Coffee or tea drinking was defined as drinking the beverage at least 4 days/week for 3 months. Heavy coffee or tea consumption was defined as drinking at least two cups every day.

Results: A total of 1837 participants (970 men; age 51.57 ± 10.21 years), who had data on clinical characteristics and consumption of coffee and tea with or without additives such as milk or sugar were included for final analysis. Among them, 467 (25.4%) were diagnosed as having symptomatic GERD based on the RDQ score, and 427 (23.2%) had erosive esophagitis (EE) on endoscopy. Drinking coffee or tea was not associated with reflux symptoms or EE in univariate and multivariate analyses. In contrast, drinking coffee with milk was associated with reflux symptoms and drinking "tea and coffee" was associated with EE in univariate analysis. However, these associations became insignificant after multivariate analysis.

Conclusion: Drinking coffee or tea and adding milk or sugar was not associated with reflux symptoms or EE.

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