Cassandra Jennings, Savannah Gosnell, Kaylah N Curtis, Thomas Kosten, Ramiro Salas
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引用次数: 2
摘要
本研究旨在探讨吸烟退伍军人的habenular静息状态功能连接(RSFC)异常。作者研究了完全吸烟者(n = 3D 18)、夜间剥夺吸烟者(n = 3D 13)和非吸烟者(n = 3D 26)的RSFC。种子-体素分析用于探索缰核中的RSFC。与不吸烟的人相比，不吸烟的人在右缰核和两个体素簇(一个在右侧梭状回，一个在左侧舌回)之间表现出更高的RSFC。为了研究尼古丁戒断，作者使用Shiffman-Jarvik戒断问卷(SJWQ)评分作为回归因子，发现与戒烟者相比，戒烟者的右缰和左额极之间的RSFC更高。当使用SJWQ作为回归因子时，右habenula RSFC区分了正常吸烟者和被剥夺吸烟者，并区分了正常吸烟者和被剥夺吸烟者，提示habenula在烟草戒断中起作用。
Altered habenula resting state functional connectivity in deprived veteran tobacco smokers: A pilot study.
This study aimed to examine habenular resting state functional connectivity (RSFC) abnormalities in tobacco-smoking veterans. The authors explored RSFC in sated smokers (n = 3D 18), overnight deprived smokers (n = 3D 13), and nonsmoker controls (n = 3D 26). Seed-to-voxel analysis was used to explore RSFC in the habenula. Compared to sated smokers, deprived smokers demonstrated higher RSFC between the right habenula and two clusters of voxels: one in the right fusiform gyrus, and one in the left lingual gyrus. To study nicotine withdrawal, the authors used the Shiffman-Jarvik Withdrawal Questionnaire (SJWQ) score as a regressor and found higher RSFC between the right habenula and the left frontal pole in deprived compared to sated smokers. Right habenula RSFC distinguished between sated and deprived smokers and differentiated between sated and deprived smokers when using SJWQ as a regressor, suggesting a habenular role in tobacco withdrawal.
期刊介绍：
The Bulletin of the Menninger Clinic offers a psychodynamic perspective on the application of theory and research in outpatient psychotherapy, attachment theory, developments in cognitive neuroscience and psychopathologies, as well as the integration of different modes of therapy. This widely indexed, peer-reviewed journal has been published since 1936 by the Menninger Clinic. Topical issues focus on critical subjects such as disordered attachments, panic disorder, trauma, and evidence-based interventions.
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